Phospholipid Scramblase 1 (PLSCR1) was initially characterized as a type II
transmembrane protein involved in bilayer movements of phospholipids across the plasma …

Phospholipid scramblase 1 (PLSCR1) is a Ca2+-binding, endofacial plasma membrane
protein thought to contribute to the transbilayer movement of phosphatidylserine and other …

Phospholipid scramblase 1 (PLSCR1) is an endofacial plasma membrane protein proposed
to participate in transbilayer movement of phosphatidylserine and other phospholipids. In …

Phosphatidylserine (PS) in quiescent cells is predominantly confined to the inner leaflet of
the plasma membrane. Externalization of PS is a marker of apoptosis, exocytosis, and some …

Interferons (IFNs) mediate their diverse biologic activities through induction of the
expression of multiple genes. Whereas the mode of action of certain of these IFN-regulated …

Abstract Phospholipid scramblase 1 (PLSCR1) is the most studied protein of the scramblase
family. Originally, it was identified as a membrane protein involved in maintaining plasma …

We have identified physical and functional interactions between the epidermal growth factor
(EGF) receptor and phospholipid scramblase 1 (PLSCR1), an endofacial plasma membrane …

ABSTRACT PLSCR1−/− mice exhibit normal, steady-state hematologic parameters but
impaired emergency granulopoiesis upon in vivo administration of G-CSF. The mechanism …

Phospholipid (PL) scramblase is a 35 kDa protein that is thought to mediate Ca2+-induced
bidirectional transbilayer movement of plasma membrane phospholipids in activated …

Phospholipid scramblases are a group of homologous proteins that are conserved in all
eukaryotic organisms. They are believed to be involved in destroying plasma membrane …