Differential inductive profiles of hepatic cytochrome P450s by the extracts of Sophora flavescens in male and female C57BL/6JNarl mice

YF Ueng, CC Chen, CC Tsai, P Souček - Journal of ethnopharmacology, 2009 - Elsevier
AIM OF THE STUDY: Sophora flavescens has been used as an antipyretic and analgesic
agent. To assess the possible herb–drug interaction, effects of S. flavescens extracts on …

Inhibition of Cytochrome P450 Activities by Sophora flavescens Extract and Its Prenylated Flavonoids in Human Liver Microsomes

D Yim, MJ Kim, Y Shin, SJ Lee… - Evidence‐based …, 2019 - Wiley Online Library
Sophora flavescens possesses several pharmacological properties and has been widely
used for the treatment of diarrhea, inflammation, abscess, dysentery, and fever in East Asian …

Induction of hepatic cytochrome P450s by the herbal medicine Sophora flavescens extract in rats: impact on the elimination of theophylline

YF Ueng, CC Tsai, WS Lo, CH Yun - Drug Metabolism and …, 2010 - Elsevier
The roots of Sophora flavescens (Sf) have been widely used as a herbal medicine for the
treatment of diarrhea, gastrointestinal hemorrhage, and eczema. Cytochrome P450 (P450) …

[HTML][HTML] Effect of radix sophorae flavescentis on activity of CYP450 isoforms in rats

L Chen, J Cai, S Wang, L Hu, X Yang - International Journal of …, 2015 - ncbi.nlm.nih.gov
Abstract Kushen (Radix Sophorae Flavescentis) is the dried roots of Sophora Flavescens
Ait, alkaloids and flavonoids are the main active constituents of Radix Sophorae …

[HTML][HTML] Effect of Radix Sophorae Tonkinensis on the activity of cytochrome P450 isoforms in rats

J Cai, J Ma, K Xu, G Gao, Y Xiang… - International Journal of …, 2015 - ncbi.nlm.nih.gov
Abstract Radix Sophorae Tonkinensis (S. tonkinensis) is the processed lateral root of
Sophora subprostrata (Leguminosae) that widely distributed over the southwest China …

The influence of Rooibos (Aspalathus linearis) on adrenal steroidogenic P450 enzymes

H Perold - 2009 - scholar.sun.ac.za
This study: 1. Describes the preparation of unfermented and fermented rooibos methanol
and aqueous extracts. 2. Investigates the influence of unfermented and fermented rooibos …

Human microsomal cyttrochrome P450-mediated reduction of oxysophocarpine, an active and highly toxic constituent derived from Sophora flavescens species, and …

L Wu, W Zhong, J Liu, W Han, S Zhong, Q Wei, S Liu… - Fitoterapia, 2015 - Elsevier
Oxysophocarpine (OSC), an active and toxic quinolizidine alkaloid, is highly valued in
Sophora flavescens Ait. and Subprostrate sophora Root. OSC is used to treat inflammation …

Impact of Andrographis paniculata crude extract on mouse hepatic cytochrome P450 enzymes

K Jarukamjorn, K Don-in, C Makejaruskul… - Journal of …, 2006 - Elsevier
Modulatory influence of Andrographis paniculata crude extract on cytochrome P450 (CYP)
enzymes was performed by administration of the crude extract of Andrographis paniculata to …

In vitro effects of active constituents and extracts of Orthosiphon stamineus on the activities of three major human cDNA-expressed cytochrome P450 enzymes

Y Pan, BA Abd-Rashid, Z Ismail, R Ismail… - Chemico-biological …, 2011 - Elsevier
Orthosiphon stamineus (OS) has been traditionally used to treat diabetes, kidney and
urinary disorders, high blood pressure and bone or muscular pain. To assess the possibility …

Modulatory effects of extracts of vinegar-baked Radix Bupleuri and saikosaponins on the activity of cytochrome P450 enzymes in vitro

T Yu, X Chen, Y Wang, R Zhao, S Mao - Xenobiotica, 2014 - Taylor & Francis
In this article, the modulatory effects of extracts from vinegar-baked Radix Bupleuri (VBRB)
and saikosaponins on the activity of CYP1A2, CYP2C9 and CYP3A4 were investigated in …