ETHNO PHARMACOLOGICAL RELEVANCE: Andrographis paniculata (AP), Centella
asiatica (CA) and Orthosiphon stamineus (OS) are three popular herbs traditionally used …

Sophora flavescens (SF) is an herbal medicine widely used for the treatment of viral
hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage, and skin diseases. It was …

Objectives A novel anxiolytic natural health product (NHP) containing Souroubea sympetala
and Platanus occidentalis is available for the companion animal market and is currently …

Flavonoids are a class of dietary phytochemicals that modulate various biological activities.
The effects of flavone and five hydroxylated derivatives on the methoxyresorufin O …

Although Sophorae radix (SR) has been traditionally used as a treatment for various clinical
symptoms, a comprehensive investigation of its safety has not yet been carried out …

St. John's wort extract (SJW)(Hypericum perforatum L.) is among the most commonly used
herbal medications in the United States. The predominance of clinical reports indicates that …

The leguminosae of Sophora moorcroftiana (Benth.) Benth. ex Baker is a drought-resistant
endemic Sophora shrub species from the Qinghai-Tibet Plateau, and its seeds have …

Chalepensin, a furanocoumarin, is present in several medicinal Rutaceae plants and
causes a mechanism-based inhibition of human and mouse cytochrome P450 (P450, CYP) …

Isofraxidin is a Coumarin compound widely distributed in plants, such as the Umbelliferae or
Chloranthaceae, and it possesses numerous pharmacological activities. However, whether …

Some of the components found in herbs may be inhibitors or inducers of cytochrome P450
enzymes, which may therefore result in undesired herb-drug interactions. As a component …