Effects of sulfur-fumigation on the pharmacokinetics, metabolites and analgesic activity of Radix Paeoniae Alba
M Kong, HH Liu, J Wu, MQ Shen, ZG Wang… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance Radix Paeoniae Alba (Baishao, BS), one of the
most commonly used traditional Chinese medicinal herbs, has many pharmacological …
most commonly used traditional Chinese medicinal herbs, has many pharmacological …
Species difference in the metabolism of mulberrin in vitro and its inhibitory effect on cytochrome P450 and UDP-glucuronosyltransferase enzymes
J Hu, T Hu, Z Guo, Y Song, L Shan… - Chemical and …, 2022 - jstage.jst.go.jp
This study aimed to evaluate the interspecies difference in metabolism of mulberrin and
examine the interaction between mulberrin and CYP enzymes or recombinant human …
examine the interaction between mulberrin and CYP enzymes or recombinant human …
Short term treatment with St. John's wort, hypericin or hyperforin fails to induce CYP450 isoforms in the Swiss Webster mouse
BJ Bray, NJ Brennan, NB Perry, DB Menkes… - Life sciences, 2002 - Elsevier
This investigation was designed to determine whether St. John's wort (SJW)(435 mg/kg/d), a
readily available antidepressant, or its purported active constituents hypericin (1 mg/kg/d) …
readily available antidepressant, or its purported active constituents hypericin (1 mg/kg/d) …
Effects of phillyrin and forsythoside A on rat cytochrome P450 activities in vivo and in vitro
Y Cheng, X Liang, L Feng, D Liu, M Qin, S Liu, G Liu… - Xenobiotica, 2017 - Taylor & Francis
Phillyrin and forsythoside A are two important active ingredients in Forsythia suspensa.
However, the effects of phillyrin and forsythoside A on the activities of cytochrome P450 …
However, the effects of phillyrin and forsythoside A on the activities of cytochrome P450 …
The potential of Sutherlandia frutescens for herb-drug interaction
PS Fasinu, H Gutmann, H Schiller, AD James… - Drug Metabolism and …, 2013 - ASPET
In Africa, Sutherlandia frutescens is a popular medicinal herb widely consumed by people
living with human immunodeficiency virus/AIDS. Concomitant use with antiretroviral drugs …
living with human immunodeficiency virus/AIDS. Concomitant use with antiretroviral drugs …
In Vitro Gender‐Dependent Inhibition of Porcine Cytochrome P450 Activity by Selected Flavonoids and Phenolic Acids
B Ekstrand, MK Rasmussen, F Woll… - BioMed Research …, 2015 - Wiley Online Library
We investigated gender‐related differences in the ability of selected flavonoids and phenolic
compounds to modify porcine hepatic CYP450‐dependent activity. Using pools of …
compounds to modify porcine hepatic CYP450‐dependent activity. Using pools of …
In vitro inhibition of human cytochrome P450 enzymes by licoisoflavone B from Glycyrrhiza uralensis Fisch. ex DC
L Chen, D Nikolic, G Li, J Liu… - Toxicological …, 2023 - academic.oup.com
Glycyrrhiza uralensis Fisch. ex DC, one of the 3 pharmacopeial species of licorice and
widely used in dietary supplements, can inhibit certain cytochrome P450 (CYP) enzymes …
widely used in dietary supplements, can inhibit certain cytochrome P450 (CYP) enzymes …
Alkaloids and saponins as cytochrome P450 inhibitors from blue cohosh (Caulophyllum thalictroides) in an in vitro assay
Blue cohosh, Caulophyllum thalictroides (L.) Michx. is a popular herb, roots and rhizomes of
which have been extensively used for women's health. Alkaloids and saponins are …
which have been extensively used for women's health. Alkaloids and saponins are …
Effects of flavonoids isolated from Scutellariae radix on cytochrome P-450 activities in human liver microsomes
A series of flavonoids isolated from Scutellariae radix were evaluated for their effects on
cytochrome P-450 (CYP) activities in human liver microsomes. All flavonoids did not …
cytochrome P-450 (CYP) activities in human liver microsomes. All flavonoids did not …
Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide
D Pekthong, H Martin, C Abadie, A Bonet… - Journal of …, 2008 - Elsevier
The inhibitory effect of Andrographis paniculata extract (APE) and andrographolide (AND),
the most medicinally active phytochemical in the extract, on hepatic cytochrome P450s …
the most medicinally active phytochemical in the extract, on hepatic cytochrome P450s …