Liposomal delivery systems have significantly enhanced the efficacy and safety of
chemotherapeutic agents compared to free (non-liposomal) formulations. Liposomes are …

Doxorubicin is a potent antineoplastic agent with activity against numerous human cancers.
Encapsulation of doxorubicin inside a liposome alters bioavailability, biodistribution and …

Cancer is still a major threat to human life that is characterized by abnormal proliferation and
metastasis of cancer cells. Chemotherapy is procedure of using anti-cancer drugs for …

Liposomes are a unique platform for drug delivery, and a number of liposomal formulations
have already been commercialized. Doxil is a representative example, which uses …

The pharmacokinetics of liposome-encapsulated drugs are controlled by the interplay of two
variables: the rate of plasma clearance of the liposome carrier, and the stability of the …

Coating of liposomes with polyethylene-glycol (PEG) by incorporation in the liposome
bilayer of PEG-derivatized lipids results in inhibition of liposome uptake by the reticulo …

Doxorubicin is a widely used chemotherapy agent. Despite its utility, several adverse side
effects, especially its irreversible cardiotoxicity and reversible nephrotoxicity, have prompted …

Surface functionalization of liposomes can play a key role in overcoming the current
limitations of nanocarriers to treat solid tumors, ie, biological barriers and physiological …

Liposomes are very useful biocompatible tools used in diverse scientific disciplines,
employed for the vehiculation and delivery of lipophilic, ampiphilic or hydrophilic …

Pegylated liposomal doxorubicin (doxorubicin HCl liposome injection; Doxil® or Caelyx®) is
a liposomal formulation of doxorubicin, reducing uptake by the reticulo-endothelial system …