Acetaldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme detoxifying
acetaldehyde and endogenous lipid aldehydes; previous studies suggest a protective role of …

Abstract Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the
detoxification of alcohol-derived acetaldehyde and endogenous aldehydes. The inactivating …

Previous evidence has indicated a beneficial role for aldehyde dehydrogenase 2 (ALDH2)
in suppressing atherosclerotic plaque progression and instability. However, the underlying …

Simple Summary ALDH2, mitochondrial aldehyde dehydrogenase 2, is a critical enzyme
involved in ethanol clearance in acetaldehyde metabolism. The prevalence of the ALDH2* 2 …

Previous studies demonstrated that aldehyde dehydrogenase 2 (ALDH2) rs671
polymorphism, which eliminates ALDH2 activity down to 1%-6%, is a susceptibility gene for …

Abstract Aldehyde dehydrogenase 2 (ALDH2) is a non-cytochrome P450 mitochondrial
aldehyde oxidizing enzyme. It is best known for its role in the metabolism of acetaldehyde, a …

Background: Clinical studies show that the most common single-point mutation in humans,
ALDH2 (aldehyde dehydrogenase 2) rs671 mutation, is a risk factor for the development and …

Abstract Aldehyde dehydrogenase 1B1 (ALDH1B1) is a mitochondrial enzyme sharing 65%
and 72% sequence identity with ALDH1A1 and ALDH2 proteins, respectively. Compared to …

HMG-CoA reductase (HMGCR) is the rate-limiting enzyme in cholesterol biosynthesis and
the target for cholesterol-lowering therapy. Acetaldehyde dehydrogenase 2 (ALDH2) is …

A family of detoxifying enzymes called aldehyde dehydrogenases (ALDHs) has been a
subject of recent interest, as its role in detoxifying aldehydes that accumulate through …