Objectives: To determine the annual rates of volumetric change of the hippocampus and
temporal horn in cognitively normal elderly control subjects and individually matched …

Objective: To establish the progression of brain atrophy rates in patients with a known date
of onset of Alzheimer disease (AD). Methods: Each of 18 subjects had two high-resolution …

Objective To determine initial locus and rate of degeneration of temporal lobe structures
(total lobe, hippocampus and parahippocampus) in preclinical dementia. Background …

Hippocampal atrophy is a marker of Alzheimer disease (AD). It remains unclear whether this
holds true for younger patients as well. Hippocampal volume was measured on MRI scans …

Objective: To test the hypothesis that entorhinal cortex (EC) volume decreases at a slower
rate than the hippocampal (HC) volume in healthy adults, and to examine whether the rate of …

Background: The cognitive continuum in the elderly population can be conceptually divided
into those who are functioning normally (control subjects), those with a mild cognitive …

Objective: To evaluate the spatial pattern and regional rates of neocortical atrophy from
normal aging to early Alzheimer disease (AD). Methods: Longitudinal MRI data were …

Objective: To correlate different methods of measuring rates of brain atrophy from serial MRI
with corresponding clinical change in normal elderly subjects, patients with mild cognitive …

Magnetic resonance imaging (MRI)-based volumetric measurements of medial temporal
lobe (MTL) structures can discriminate between normal elderly control subjects and patients …

Objective: To investigate the added value of hippocampal atrophy rates over whole brain
volume measurements on MRI in patients with Alzheimer disease (AD), patients with mild …