Highlights•Hematopoietic progenitors are interconnected by F-actin-dependent TNTs.•Cell
dislodgement is the primary mechanism responsible for TNT biogenesis.•TNTs emerge from …

Acute lymphoblastic leukemia (ALL) cells reside in the bone marrow microenvironment
which nurtures and protects cells from chemotherapeutic drugs. The disruption of cell-cell …

Tunneling nanotubes (TNTs) play an important role in cell–cell communication. TNTs have
been predominantly reported among cells in monolayer culture. Using various imaging …

Acute lymphoblastic leukemia (ALL) cells disrupt the healthy bone marrow
microenvironment to create a leukemic niche that is crucial for facilitating leukemogenesis …

Tunneling nanotubes (TNT) are dynamic connections between cells, which represent a
novel route for cell-to-cell communication. A growing body of evidence points TNT towards a …

Tunneling nanotubes (TNTs) are long intercellular connecting structures providing a special
transport route between two neighboring cells. To date TNTs have been reported in different …

The interaction between tumor cells and macrophages is crucial in promoting tumor invasion
and metastasis. In this study, we examined a novel mechanism of intercellular …

Organelle exchange between cells via tunneling nanotubes (TNTs) is a recently described
form of intercellular communication. Here, we show that the selective elimination of filopodia …

Tunneling nanotubes (TNTs) are thin membranous channels providing direct cytoplasmic
connection between remote cells. They are commonly observed in different cell cultures and …

Tunneling nanotubes (TNTs) are cellular extensions enabling cytosol-to-cytosol intercellular
interaction between numerous cell types including macrophages. Previous studies of …