Impact of the implementation of a Sepsis Code hospital protocol in antibiotic prescription and clinical outcomes in an intensive care unit

L García-López, S Grau-Cerrato… - Medicina Intensiva …, 2017 - Elsevier
Introduction A study is conducted on the impact of a Sepsis Code Hospital Protocol upon
antibiotic use, hospital stay and mortality. Design A quasi-experimental, retrospective …

[HTML][HTML] Timing of antibiotics in septic patients: a prospective cohort study

H Seok, J Song, JH Jeon, HK Choi, WS Choi… - Clinical Microbiology …, 2020 - Elsevier
Objectives To evaluate the effect of timing and appropriateness of antibiotics administration
on mortality in patients diagnosed with sepsis according to the Sepsis-3 definition. Methods …

Pharmacokinetics and pharmacodynamics of antibiotics in critically ill acute kidney injury patients

W Zamoner, FM de Freitas, DSS Garms… - Pharmacology …, 2016 - Wiley Online Library
Sepsis is the most common cause of death in critically ill patients and is associated with
multiorgan failure, including acute kidney injury (AKI). This situation can require acute renal …

Time to antibiotic administration independently predicts survival from severe sepsis in patients treated according to the surviving sepsis guidelines

GJ Fulda, M Zubrow, T Dahanayake, D Mahoney… - Chest, 2007 - journal.chestnet.org
PURPOSE: The mortality of severe sepsis exceeds 40%. Recently, the treatment of severe
sepsis has focused on management guidelines which incorporate multiple therapeutic …

Does nonadherence to local recommendations for empirical antibiotic therapy on admission to the intensive care unit have an impact on in-hospital mortality?

JL Baudel, J Tankovic, F Carrat, C Vigneau… - … and clinical risk …, 2009 - Taylor & Francis
Objective 1/To evaluate if empirical antibiotic prescription on admission to our intensive care
unit (ICU) respects the local recommendations for antibiotic prescription and to identify …

Appropriateness of antibiotic prescribing for patients with sepsis in rural hospital emergency departments

AJ Heffernan, A Smedley, T Stickley… - Australian Journal of …, 2024 - Wiley Online Library
Abstract Design/Participants This was a multicentre retrospective cohort study of adult
patients (≥ 18 years) presenting with a process associated International Classification of …

Appropriateness of diagnosis and antibiotic use in sepsis patients admitted to a tertiary hospital in Indonesia

F Ginting, AK Sugianli, M Barimbing… - Postgraduate …, 2021 - Taylor & Francis
Objective To evaluate the diagnostic and antibiotic treatment strategies for patients
suspected of sepsis, in a tertiary hospital in Indonesia. This can identify areas for …

Impact of inappropriate empiric antimicrobial therapy on mortality of septic patients with bacteremia: a retrospective study

S Lueangarun, A Leelarasamee - … Perspectives on Infectious …, 2012 - Wiley Online Library
Background. Inappropriate empiric antimicrobials could be a major cause of unfavorable
mortality rates in co‐morbid patients. This study aimed to assess the prevalence and impact …

Determinants of Inadequate Empiric Antimicrobial Therapy in ICU Sepsis Patients in Al-Madinah Al-Munawwarah, Saudi Arabia: A Comparison of Artificial Neural …

AHH Dala Ali, SN Harun, N Othman, B Ibrahim… - Antibiotics, 2023 - mdpi.com
In the management of sepsis, providing adequate empiric antimicrobial therapy is one of the
most important pillars of sepsis management. Therefore, it is important to evaluate the …

Impact of a hospital sepsis management protocol on the selection of empirical antibiotics in infectious disease consultations

A Özden, B Dalgıç, M Demir, G Hazırolan… - Journal of …, 2024 - Taylor & Francis
It is well-established that Infectious Diseases consultation (IDC) enhances the prognosis of
bloodstream infections. However, it is unclear if adoption of an institutional sepsis protocol …