Objectives To assess benefits and harms of empirical mono-vs. combination antibiotic
therapy in adult patients with severe sepsis in the intensive care unit (ICU). Methods We …

Considerable evidence has shown that adequate antibiotic therapy is of utmost importance
in the critically ill septic patient. However, antibiotic concentration may be insufficient early in …

Objective: The aim of the present study was to identify antibiotics prescribing patterns for
patients admitted to ICU at King Faisal Medical Complex (KFMC), Taif, Saudi Arabia to …

Objectives To investigate the association between the timing and adequacy of antibiotics
administered to patients presenting with culture‐positive sepsis and septic shock to the ED …

Severe sepsis often leads to multiple organ dysfunction syndromes (MODS) with acute
kidney injury (AKI). AKI affects approximately, 35% of Intensive Care Unit patients, and most …

Background. The emergence of multidrug-resistant, extensively resistant and pan-resistant
pathogens and the widespread inappropriate use of antibiotics is a global catastrophe …

Retrospective study was conducted in surgical intensive care unit (ICU) in Clinical Hospital
Center Zagreb in 2005. The aim of study was to create guidelines for empirical antibiotic …

Objectives: To assess the mortality benefits of timely antibiotic treatment of adults present at
the emergency department with sepsis and compare one-hour administration and 3-hour …

PURPOSE: The purpose of the study was to investigate whether a novel assay of antibiotic
efficacy could predict clinical outcome measures in septic patients in the intensive care unit …

Intensive care unit (ICU)-acquired infection is a common cause of poor prognosis of sepsis
in ICU. However, sepsis-associated ICU-acquired infections have not been fully …