Finite element simulations of hyperpolarized gas DWI in micro‐CT meshes of acinar airways: validating the cylinder and stretched exponential models of lung …

HF Chan, GJ Collier, J Parra‐Robles… - Magnetic Resonance in …, 2021 - Wiley Online Library
Purpose This work assesses the accuracy of the stretched exponential (SEM) and cylinder
models of lung microstructural length scales that can be derived from hyperpolarized gas …

Development of a Three-Dimensional Visualization and Atlasing Tool for Pulmonary Gas Distribution from Hyperpolarized 3He Magnetic Resonance Imaging

A Wheatley, U Aladl, I Gyacskov, A Fenster, G Parraga - archive.ismrm.org
Until the emergence of hyperpolarized 3He MRI, it has been difficult to quantify and visualize
the structure/function relationships of the lung with high spatial and temporal resolution. Our …

[引用][C] Assessment of ventilation heterogeneity using hyperpolarized gas MRI histogram analysis

PJC Hughes, L Smith, F Horn… - Proceedings of the …, 2018 - archive.ismrm.org
Development of sensitive imaging biomarkers to differentiate health from disease is an
important research topic in pulmonary MRI. This work aimed to make use of the rich spatial …

Evaluation of emphysema severity and progression in a rabbit model: comparison of hyperpolarized 3He and 129Xe diffusion MRI with lung morphometry

JF Mata, TA Altes, J Cai, K Ruppert… - Journal of applied …, 2007 - journals.physiology.org
The apparent diffusion coefficients (ADCs) of hyperpolarized 3He and 129Xe gases were
measured in the lungs of rabbits with elastase-induced emphysema and correlated against …

Exploration of multi-volumetric hyperpolarized 3helium MRI: Cross-correlation with quantitative MDCT

AF Halaweish - 2011 - search.proquest.com
Abstract Hyperpolarized 3Helium (HP 3 He) magnetic resonance imaging (MRI) has
provided considerable insights into the anatomical structures and localized physiological …

Quantitation of Pulmonary Structure via Registration and Normalization of Serial 3He MR Images

T Sundaram, J Gee, P Burstein, B Avants… - archive.ismrm.org
MR imaging of inhaled hyperpolarized helium has been shown to provide reproducible
measures of lung structure. This work demonstrates that registration can be performed both …

Optimal strategy for b-values selection for lung morphometry with hyperpolarized 3He diffusion MRI

AL Sukstanskii, JD Quirk, MS Conradi… - Proc. Intl. Soc. Mag …, 2009 - archive.ismrm.org
Lung morphometry with hyperpolarized 3He diffusion MRI allows estimation of lung
microstructural parameters. Herein Bayesian analysis is used to analyze how the accuracy …

Validation of Hyperpolarized 3Helium MRI in Probing Regional Ventilation: A Quantitative Assessment Against MDCT Based Local Air Volume Changes (AVC)

AF Halaweish, Y Yin, DR Thedens, CL Lin… - archive.ismrm.org
Hyperpolarized 3 Helium MRI has enabled probing of ventilation distribution (static
ventilation) and the underlying microstructure (apparent diffusion coefficients). We have …

[引用][C] SUNRISE EDUCATIONAL COURSE

MDA Yablonskiy

Diffusion lung imaging with hyperpolarized gas MRI

DA Yablonskiy, AL Sukstanskii, JD Quirk - NMR in Biomedicine, 2017 - Wiley Online Library
Lung imaging using conventional 1H MRI presents great challenges because of the low
density of lung tissue, lung motion and very fast lung tissue transverse relaxation (typical T2 …