The difference in ventilation heterogeneity between asthmatic and healthy subjects quantified using hyperpolarized 3He MRI

YS Tzeng, K Lutchen, M Albert - Journal of applied …, 2009 - journals.physiology.org
In this pilot study, algorithms for quantitatively evaluating the distribution and heterogeneity
of human ventilation imaged with hyperpolarized (HP) 3He MRI were developed for the goal …

[引用][C] Microstructural function in the lung: static and dynamic studies of ventilation and diffusion using hyperpolarized helium-3 MRI at two field strengths

KA Hill - 2011 - Oxford University

q‐space analysis of lung morphometry in vivo with hyperpolarized 3He spectroscopy

DD Shanbhag, TA Altes, GW Miller… - Journal of Magnetic …, 2006 - Wiley Online Library
Purpose To examine the utility of a 3He spectroscopic q‐space technique for detecting
changes in lung morphometry in vivo. Materials and Methods A diffusion‐weighted …

[引用][C] Quantification Of Ventilation Heterogeneity From Hyperpolarized 3He MRI: Relationship To Airway Hyperresponsiveness In Asthmatics

JK Lui, H Parameswaran, MS Albert… - … IN IMAGING FOR …, 2013 - atsjournals.org
METHODS: 3He-MRI images of four healthy and nine mild-to-moderate asthmatic subjects
were processed and measurements of lung resistance and lung elastance were acquired …

[图书][B] Quantitative Methods for Evaluating Ventilation on Hyperpolarized Gas MRI

KJ Carey - 2020 - search.proquest.com
Abstract Magnetic Resonance Imaging (MRI) is an attractive modality for imaging the
pulmonary system at relatively high resolution, especially for longitudinal disease …

Quantification of Hyperpolarized 3He MRI Ventilation Heterogeneity in Asthmatics: Surface Area of Ventilation Clusters

A Westcott, RL Eddy, DPI Capaldi, HM Young… - archive.ismrm.org
Ventilation heterogeneity measured using hyperpolarized noble-gas magnetic-resonance
imaging (MRI), presents a significant challenge in terms of the need for imaging processing …

Probing lung microstructure with hyperpolarized noble gas diffusion MRI: theoretical models and experimental results

DA Yablonskiy, AL Sukstanskii, JD Quirk… - Magnetic resonance …, 2014 - Wiley Online Library
The introduction of hyperpolarized gases (3He and 129Xe) has opened the door to
applications for which gaseous agents are uniquely suited—lung MRI. One of the pulmonary …

In Vivo Quantification Of Lung Morphometry In Healthy And Diseased Mice With Hyperpolarized 3he Diffusion MRI

JC Woods, W Wang, DA Yablonskiy… - A108. HOW USEFUL …, 2011 - atsjournals.org
Methods: 12-week-old C57BL/6 mice (n= 7) were anesthetized, mechanically ventilated on a
custom-built ventilator, and hyperpolarized 3 He diffusion MRI was performed at peak …

[HTML][HTML] Application of a stretched-exponential model for morphometric analysis of accelerated diffusion-weighted 129Xe MRI of the rat lung

AV Ouriadov, MS Fox, AA Lindenmaier, E Stirrat… - … Resonance Materials in …, 2021 - Springer
Abstract Objective Diffusion-weighted, hyperpolarized 129 Xe MRI is useful for the
characterization of microstructural changes in the lung. A stretched exponential model was …

Computer modelling and visualisation of the microscopic distributions of hyperpolarised gas diffusivity in models of acinar airways

J Parra-Robles, X Xu, JM Wild - 2011 - Eur Respiratory Soc
Diffusion MRI using hyperpolarized gases is sensitive to lung microstructure. Computer
simulations used to investigate the relationship between diffusivity (ADC) and airway …