Purpose To develop and test compressed sensing–based multiframe 3D MRI of grid‐tagged
hyperpolarized gas in the lung. Theory and Methods Applying grid‐tagging RF pulses to …

In an attempt to characterize ventilation heterogeneity, average local coefficient-of-variation
and standard deviation of pixel intensity have been computed for hyperpolarized 3He MR …

Magnetic resonance imaging (MRI) of the lung is challenging due to the low proton density
of lung parenchymal tissue relative to that of other soft tissue structures within the body, the …

During the measurement of hyperpolarized 129Xe magnetic resonance imaging (MRI), the
diffusion‐weighted imaging (DWI) technique provides valuable information for the …

Despite a long history of development, diagnostic tools for in vivo regional assessment of
lungs in patients with pulmonary emphysema are not yet readily available. Recently, a new …

Introduction: Two models of gas diffusion MRI, namely the cylinder model (CM)[Yablonskiy,
DA, et al.(2002). PNAS 99 (5)] and the stretched exponential model (SEM)[Parra-Robles, J …

Asthma and chronic obstructive pulmonary disease (COPD) are characterized by airflow
limitations resulting from airway obstruction and/or tissue destruction. The diagnosis and …

Hyperpolarized 3 He gas allows the air spaces of the lungs to be imaged via MRI. Imaging of
restricted diffusion is addressed here, which allows the microstructure of the lung to be …

Purpose Lung morphometry with hyperpolarized gas diffusion MRI is a highly sensitive
technique for the noninvasive measurement of acinar microstructural parameters …

The 3He lung morphometry technique (Yablonskiy et al., JAP, 2009), based on MRI
measurements of hyperpolarized gas diffusion in lung airspaces, provides unique …