Hyperpolarized helium-3 (3 He) magnetic resonance imaging (MRI) has emerged as a non-
invasive research method for quantifying lung structural and functional changes, enabling …

Introduction Despite the excellent functional sensitivity of hyperpolarised gas MRI to early
lung disease, clinical uptake of the technique has to date been hindered by patents …

This work seeks to provide a quantitative regional measure of gas retention in the lung. A 3D
multi-echo projection acquisition is used, accompanied with an iterative HYPR …

Rationale: In order for HP MRI-derived regional parameters to produce meaningful
information for the characterization of lung disorders, it is essential to execute a …

Hyperpolarized gas magnetic resonance imaging has been explored extensively as a
promising tool for the quantitative evaluation of regional pulmonary pathophysiology. This …

In a recently published paper by Parra-Robles and Wild [1], the authors challenge the in vivo
lung morphometry technique (based on hyperpolarized gas diffusion MRI) developed by our …

Hyperpolarized 3 Helium MRI Apparent Diffusion Coefficient (ADC) measurements enable
probing of the lung microstructure and evaluation of pathological processes that affect …

Introduction and objectives Magnetic resonance (MR) imaging of the hyperpolarised noble
gases 3 He and 129 Xe provides exquisite depiction of pulmonary ventilation. In addition …

Rationale: Data driven computational models may provide detailed insight on distribution of
ventilation beyond the spatial resolution of current state-of-the-art imaging modalities …

Diffusion-weighted hyperpolarized 129 Xe MRI is a validated measure of lung microstructure
and can assess changes in alveolar dimensions. These images are commonly acquired via …