Background Glucocorticoids are often used in the treatment of nonhematologic malignancy.
This review summarizes the clinical evidence of the effect of glucocorticoid therapy on …

Glucocorticoids are steroidal hormones which exert their action via genomic and non-
genomic mechanisms. In the clinical setting, glucocorticoids are utilized for their anti …

Glucocorticoids play an essential role in embryonic development and tissue homeostasis
and possess important antiinflammatory and immunosuppressive properties. Due to their …

Glucocorticoids (GCs) are anti-inflammatory and immunosuppressive steroid molecules
secreted by the adrenal gland and regulated by the hypothalamic–pituitary–adrenal (HPA) …

DECLAN WALSH, MSc., AND JAY AVASHIA, MD n Glucocorticoids have been used in
clinical oncology for more than three decades. Their anti-inflammatory action plays a major …

Glucocorticoids have been used for a substan-tial period to treat patients with advanced
androgen-independent prostate cancer (AIPC). Although known for their anti-inflammatory …

Unlike other steroid hormone receptors, the glucocorticoid receptor (GR) is not considered
an oncogene. In breast cancer, the estrogen receptor (ER) drives cell growth, proliferation …

Background: Glucocorticoids are widely used for cancer patients, although they can reduce
the efficacy of anticancer treatment. Materials and Methods: We characterized non-apoptotic …

Purpose Corticosteroids are commonly used in palliative care settings, but are associated
with several side effects. Although adverse events (AEs) are highly distressing for patients …

Background Glucocorticoids could theoretically decrease breast cancer risk through their
anti-inflammatory effects or increase risk through immunosuppression. However …