Zip14 is a member of the SLC39A zinc transporter family, which is involved in zinc uptake by
cells. Up-regulation of Zip14 by IL-6 appears to contribute to the hepatic zinc accumulation …

ZnT2 (zinc transporter-2) expression is restricted to tissues with unique zinc requirements
such as mammary and prostate glands. We previously determined that ZnT2 plays a major …

The second abundant micronutrient, zinc, is attracting more and more attention for it
performs essential functions in living organisms and bears close relationships with the …

Zinc is an essential micronutrient that plays critical roles in numerous physiological
processes, including bone homeostasis. The majority of zinc in the human body is stored in …

Zinc transporter 1 (ZNT1) is the only zinc transporter predominantly located on the plasma
membrane, where it plays a pivotal role exporting cytosolic zinc to the extracellular space …

The SLC30 family of cation diffusion transporters includes at least nine members in
mammals, most of which have been documented to play a role in zinc transport. The …

Abstract Zinc transporters, the Zrt-, Irt-like protein (ZIP) family and the Zn transporter (ZnT)
family transporters, are found in all aspects of life. Increasing evidence has clarified the …

Intracellular zinc homeostasis is strictly regulated by zinc binding proteins and zinc
transporters. In the present study, we quantified in a first global view the expression of all …

Copper is a vital mineral for many organisms, yet it is highly toxic as demonstrated by
serious health concerns associated with its deficiency or excess accumulation. The SLC31 …

A novel autosomal recessive cerebro-renal syndrome was identified in consanguineous
Bedouin kindred: neurological deterioration was evident as of early age, progressing into …