Cellular activation pathways and interaction networks in vascularized composite allotransplantation
Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive
surgery that has revolutionized the treatment of patients with devastating injuries, including …
surgery that has revolutionized the treatment of patients with devastating injuries, including …
Mechanisms and mediators of inflammation: potential models for skin rejection and targeted therapy in vascularized composite allotransplantation
T Hautz, D Wolfram, J Grahammer… - Journal of …, 2012 - Wiley Online Library
Vascularized composite allotransplantation (VCA) is an effective treatment option for
patients suffering from limb loss or severe disfigurement. However, postoperative courses of …
patients suffering from limb loss or severe disfigurement. However, postoperative courses of …
Immunological and inflammatory mapping of vascularized composite allograft rejection processes in a rat model
Background Hand and face vascularized composite allotransplantation (VCA) is an evolving
and challenging field with great opportunities. During VCA, massive surgical damage is …
and challenging field with great opportunities. During VCA, massive surgical damage is …
Composite tissue allotransplantation: opportunities and challenges
J Iske, Y Nian, R Maenosono, M Maurer… - Cellular & molecular …, 2019 - nature.com
Vascularized composite allotransplants (VCAs) have unique properties because of diverse
tissue components transplanted en mass as a single unit. In addition to surgery, this type of …
tissue components transplanted en mass as a single unit. In addition to surgery, this type of …
Large animal models of vascularized composite allotransplantation: a review of immune strategies to improve allograft outcomes
AJ Matar, RL Crepeau, GS Mundinger… - Frontiers in …, 2021 - frontiersin.org
Over the past twenty years, significant technical strides have been made in the area of
vascularized composite tissue allotransplantation (VCA). As in solid organ transplantation …
vascularized composite tissue allotransplantation (VCA). As in solid organ transplantation …
Vascular signaling in allogenic solid organ transplantation–the role of endothelial cells
L Kummer, M Zaradzki, V Vijayan, R Arif… - Frontiers in …, 2020 - frontiersin.org
Graft rejection remains the major obstacle after vascularized solid organ transplantation.
Endothelial cells, which form the interface between the transplanted graft and the host's …
Endothelial cells, which form the interface between the transplanted graft and the host's …
Vascularized composite tissue allotransplantation–state of the art
JR Diaz‐Siso, EM Bueno, GC Sisk… - Clinical …, 2013 - Wiley Online Library
Vascularized composite tissue allotransplantation is a viable treatment option for injuries
and defects that involve multiple layers of functional tissue. In the past 15 yr, more than 150 …
and defects that involve multiple layers of functional tissue. In the past 15 yr, more than 150 …
Diagnosing skin rejection in vascularized composite allotransplantation: advances and challenges
Refinements in microsurgical techniques coupled with advances in immunosuppressive and
immunomodulatory protocols have enabled broader clinical application of vascularized …
immunomodulatory protocols have enabled broader clinical application of vascularized …
A systematic review of immunomodulatory strategies used in skin-containing preclinical vascularized composite allotransplant models
Background Acute rejection remains a vexing problem in vascularized composite
allotransplantation (VCA). Available immunosuppressive regimens are successful at …
allotransplantation (VCA). Available immunosuppressive regimens are successful at …
A critical analysis of rejection in vascularized composite allotransplantation: clinical, cellular and molecular aspects, current challenges, and novel concepts
Advances in microsurgical techniques and immunomodulatory protocols have contributed to
the expansion of vascularized composite allotransplantation (VCA) with very encouraging …
the expansion of vascularized composite allotransplantation (VCA) with very encouraging …