The lateral habenula and the serotonergic system
The habenula (Hb) is an epithalamic structure differentiated into two nuclear complexes,
medial (MHb) and lateral habenula (LHb). After decades of relative neglect, interest in the …
medial (MHb) and lateral habenula (LHb). After decades of relative neglect, interest in the …
Habenular connections with the dopaminergic and serotonergic system and their role in stress‐related psychiatric disorders
The habenula (Hb) is a phylogenetically old epithalamic structure differentiated into two
nuclear complexes, the medial (MHb) and lateral habenula (LHb). After decades of search …
nuclear complexes, the medial (MHb) and lateral habenula (LHb). After decades of search …
The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview
The lateral habenula (LH b) is an epithalamic region with a crucial role in the regulation of
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …
Circuits and functions of the lateral habenula in health and in disease
H Hu, Y Cui, Y Yang - Nature Reviews Neuroscience, 2020 - nature.com
The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …
owing to new discoveries relating to its critical role in regulating negatively motivated …
[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation
Over the last decade, the understanding of the habenula has rapidly advanced from being
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
Can the lateral habenula crack the serotonin code?
A Tchenio, K Valentinova, M Mameli - Frontiers in synaptic …, 2016 - frontiersin.org
The lateral habenula (LHb) and the serotonergic system both contribute to motivational
states by encoding rewarding and aversive signals. Converging evidence suggests that …
states by encoding rewarding and aversive signals. Converging evidence suggests that …
Habenula: crossroad between the basal ganglia and the limbic system
O Hikosaka, SR Sesack, L Lecourtier… - Journal of …, 2008 - Soc Neuroscience
There is a growing awareness that emotion, motivation, and reward values are important
determinants of our behavior. The habenula is uniquely positioned both anatomically and …
determinants of our behavior. The habenula is uniquely positioned both anatomically and …
The role of lateral habenula–dorsal raphe nucleus circuits in higher brain functions and psychiatric illness
H Zhao, BL Zhang, SJ Yang, B Rusak - Behavioural brain research, 2015 - Elsevier
Serotonergic neurons in the dorsal raphe nucleus (DRN) play an important role in regulation
of many physiological functions. The lateral nucleus of the habenular complex (LHb) is …
of many physiological functions. The lateral nucleus of the habenular complex (LHb) is …
Dorsal raphe projection inhibits the excitatory inputs on lateral habenula and alleviates depressive behaviors in rats
H Zhang, K Li, HS Chen, SQ Gao, ZX Xia… - Brain Structure and …, 2018 - Springer
Hypofunction of the serotonergic (5-HT) system has close relationship with the symptoms in
major depressive disorders (MDD), however, the underlying neural circuitry mechanisms are …
major depressive disorders (MDD), however, the underlying neural circuitry mechanisms are …
5HT1B receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula
EK Hwang, J Chung - Neuropharmacology, 2014 - Elsevier
Accumulating lines of evidence indicate that the lateral habenula (LHb), which reciprocally
interacts with raphe nuclei (RN), displays hyperactivity including synaptic potentiation of …
interacts with raphe nuclei (RN), displays hyperactivity including synaptic potentiation of …