Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
disorders of genetic and environmental etiologies. Some ASD cases are syndromic …

Objective: Neuroimaging studies show structural differences in both cortical and subcortical
brain regions in children and adults with autism spectrum disorder (ASD) compared with …

Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …

Autism is clearly a disorder of neural development, but when, where, and how brain
pathology occurs remain elusive. Typical brain development is comprised of several stages …

An interneuron alteration has been proposed as a source for the modified balance of
excitation/inhibition in the cerebral cortex in autism. We previously demonstrated a …

Background Cross-sectional diffusion-weighted magnetic resonance imaging studies
suggest that young autistic children have alterations in white matter structure that differ from …

Dendritic spines are small protrusions from neuronal dendrites that form the postsynaptic
component of most excitatory synapses in the brain. They play critical roles in synaptic …

Microglial activation and alterations in neuron number have been reported in autism.
However, it is unknown whether microglial activation in the disorder includes a neuron …

Autism spectrum disorder (ASD) involves deficits in speech and sound processing. Cortical
circuit changes during early development likely contribute to such deficits. Subplate neurons …

BACKGROUND: Evidence from behavioral, imaging, and postmortem studies indicates that
the frontal lobe, as well as other brain regions such as the cerebellum and limbic system …