Inhibitory and excitatory synapses play a fundamental role in information processing in the
brain. Excitatory synapses usually are situated on dendritic spines, small membrane …

Rapid progress in identifying the genes underlying autism spectrum disorder (ASD) has
provided the substrate for a first wave of analyses into the underlying neurobiology. This …

The cellular mechanism (s) underlying autism spectrum disorders (ASDs) are not fully
understood although it has been shown that various genetic and environmental factors …

Autism is a behaviorally defined disorder with deficits in social interaction, communication,
atypical behaviors, and restricted areas of interest. Postmortem studies of the brain in autism …

Dendritic spines are multifunctional integrative units of the nervous system and are highly
diverse and dynamic in nature. Both internal and external stimuli influence dendritic spine …

Autism is a condition manifested as abnormalities of relatedness, communication, range of
interests, and repetitive behaviors. Despite alarming prevalence estimates and exhortations …

Objective: Autism spectrum disorder (ASD) is accompanied by highly individualized
neuroanatomical deviations that potentially map onto distinct genotypes and clinical …

The cerebellum contains the largest number of neurons and synapses of any structure in the
central nervous system. The concept that the cerebellum is solely involved in fine motor …

Differences in cortical morphology—in particular, cortical volume, thickness and surface
area—have been reported in individuals with autism. However, it is unclear what aspects of …

Psychiatric and neurologic disorders ranging from mental retardation to addiction are
accompanied by structural and functional alterations of synaptic connections in the brain …