Brain anatomy and development in autism: review of structural MRI studies

P Brambilla, A Hardan, SU Di Nemi, J Perez… - Brain research …, 2003 - Elsevier
Autism is a neurodevelopmental disorder that severely disrupts social and cognitive
functions. MRI is the method of choice for in vivo and non-invasively investigating human …

Role of astrocyte–synapse interactions in CNS disorders

E Blanco‐Suárez, ALM Caldwell… - The Journal of …, 2017 - Wiley Online Library
Astrocytes comprise half of the cells in the brain. Although astrocytes have traditionally been
described as playing a supportive role for neurons, they have recently been recognized as …

Abnormal early brain development in autism

E Courchesne - Molecular psychiatry, 2002 - nature.com
A pivotal period in human brain and behavioral development occurs in the first years of life.
These years are normally characterized by a degree and variety of neuroanatomical change …

Minicolumnar pathology in autism

MF Casanova, DP Buxhoeveden, AE Switala, E Roy - Neurology, 2002 - AAN Enterprises
Objective: To determine whether differences exist in the configuration of minicolumns
between the brains of autistic and control patients. Background: Autism is a severe and …

[HTML][HTML] Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease

S Watanabe, T Kurotani, T Oga, J Noguchi… - Nature …, 2021 - nature.com
Autism spectrum disorder (ASD) is a multifactorial disorder with characteristic synaptic and
gene expression changes. Early intervention during childhood is thought to benefit …

Changes in the developmental trajectories of striatum in autism

M Langen, HG Schnack, H Nederveen, D Bos… - Biological …, 2009 - Elsevier
BACKGROUND: Repetitive and stereotyped behavior has been associated with striatum in
various neuropsychiatric disorders. However, striatal involvement has not yet been shown …

Cortical folding abnormalities in autism revealed by surface-based morphometry

CW Nordahl, D Dierker, I Mostafavi… - Journal of …, 2007 - Soc Neuroscience
We tested for cortical shape abnormalities using surface-based morphometry across a range
of autism spectrum disorders (7.5–18 years of age). We generated sulcal depth maps from …

Brain growth across the life span in autism: age-specific changes in anatomical pathology

E Courchesne, K Campbell, S Solso - Brain research, 2011 - Elsevier
Autism is marked by overgrowth of the brain at the earliest ages but not at older ages when
decreases in structural volumes and neuron numbers are observed instead. This has led to …

[HTML][HTML] Current knowledge on the genetics of autism and propositions for future research

T Bourgeron - Comptes rendus biologies, 2016 - Elsevier
Autism spectrum disorders (ASD) are a heterogeneous group of neuropsychiatric disorders
characterized by problems in social communication, as well as by the presence of restricted …

Abnormal cell patterning at the cortical gray–white matter boundary in autism spectrum disorders

TA Avino, JJ Hutsler - Brain research, 2010 - Elsevier
Previous research on neuronal spacing and columnar organization indicates the presence
of cell patterning alterations within the cerebral cortex of individuals with autism spectrum …