Mild hypoxic ischaemic encephalopathy and long term neurodevelopmental outcome-A systematic review

JM Conway, BH Walsh, GB Boylan, DM Murray - Early human development, 2018 - Elsevier
Aims Hypoxic ischaemic encephalopathy (HIE) remains a significant cause of long term
neurodisability despite therapeutic hypothermia (TH). Infants with mild HIE, representing …

Hypothermia for Hypoxic-ischemic Encephalopathy: Second-generation Trials to Address Gaps in Knowledge

AR Laptook, S Shankaran… - Clinics in …, 2024 - perinatology.theclinics.com
Prior to 2005, the management of hypoxic-ischemic encephalopathy (HIE) among term
newborns was limited to intensive supportive care without a specific brainoriented therapy …

Utilization of therapeutic hypothermia and neurological injury in neonates with mild hypoxic-ischemic encephalopathy: a report from children's hospital neonatal …

R Rao, U Mietzsch, R DiGeronimo… - American journal of …, 2020 - thieme-connect.com
Objective This study was aimed to describe utilization of therapeutic hypothermia (TH) in
neonates presenting with mild hypoxic-ischemic encephalopathy (HIE) and associated …

“Mild''Hypoxic-Ischaemic Encephalopathy and Therapeutic Hypothermia: A Survey of Clinical Practice and Opinion from 35 Countries

M Singla, L Chalak, K Kumar, M Hayakawa, S Mehta… - Neonatology, 2022 - karger.com
Introduction: We aimed to determine global professional opinion and practice for the use of
therapeutic hypothermia (TH) for treating infants with mild hypoxic-ischaemic …

Regional variability in therapeutic hypothermia eligibility criteria for neonatal hypoxic-ischemic encephalopathy

J Proietti, GB Boylan, BH Walsh - Pediatric Research, 2024 - nature.com
Early induced therapeutic hypothermia represents the cornerstone treatment in neonates
with probable hypoxic-ischemic encephalopathy. The selection of patients for treatment …

Childhood outcomes after hypothermia for neonatal encephalopathy

S Shankaran, A Pappas, SA McDonald… - … England Journal of …, 2012 - Mass Medical Soc
Background We previously reported early results of a randomized trial of whole-body
hypothermia for neonatal hypoxic–ischemic encephalopathy showing a significant reduction …

An observational study of therapeutic hypothermia and factors associated with mortality in late-preterm and term neonates with hypoxic-ischemic encephalopathy in a …

NY Boo, SH Neoh, SC Chee… - Frontiers in …, 2022 - frontiersin.org
Objectives To investigate the types of therapeutic hypothermia (TH) used and risk factors
associated with mortality in late-preterm and term neonates (LPTN, gestation of≥ 35 weeks) …

[HTML][HTML] Therapeutic hypothermia for neonates with hypoxic ischemic encephalopathy

MC Chiang, YJ Jong, CH Lin - Pediatrics & Neonatology, 2017 - Elsevier
Therapeutic hypothermia (TH) is a recommended regimen for newborn infants who are at or
near term with evolving moderate-to-severe hypoxic ischemic encephalopathy (HIE). The …

Implementation of neonatal neurocritical care program improved short-term outcomes in neonates with moderate-to-severe hypoxic ischemic encephalopathy

S Roychoudhury, MJ Esser, J Buchhalter… - Pediatric Neurology, 2019 - Elsevier
Background Despite the introduction of therapeutic hypothermia, infants with moderate-to-
severe hypoxic-ischemic encephalopathy remain at risk of mortality and morbidity. A …

Cooling therapy for the management of hypoxic-ischaemic encephalopathy in middle-income countries: we can, but should we?

S Thayyil - Paediatrics and International Child Health, 2019 - Taylor & Francis
In the past decade a large number of studies of cooling for the treatment of hypoxic-
ischaemic encephalopathy have been reported from middleincome countries (MIC), yet …