Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: a randomized controlled trial

SE Jacobs, CJ Morley, TE Inder… - … of pediatrics & …, 2011 - jamanetwork.com
Objective To determine the effectiveness and safety of moderate whole-body hypothermia in
newborns with hypoxic-ischemic encephalopathy born in hospitals with and without …

Neonatal hypoxic-ischemic encephalopathy and hypothermia treatment

T Arnautovic, S Sinha, AR Laptook - Obstetrics & Gynecology, 2022 - journals.lww.com
Neonatal hypoxic-ischemic encephalopathy (HIE) is an important clinical entity because it is
associated with death and long-term disability, including cognitive impairment, cerebral …

Hypothermia to treat neonatal hypoxic ischemic encephalopathy: systematic review

PS Shah, A Ohlsson, M Perlman - Archives of pediatrics & …, 2007 - jamanetwork.com
Objectives To systematically review the effectiveness, as determined by survival without
moderate to severe neurodevelopmental disability in infancy and childhood, and the safety …

Hypoxic-ischemic encephalopathy and therapeutic hypothermia: the hemodynamic perspective

RE Giesinger, LJ Bailey, P Deshpande… - The Journal of …, 2017 - jpeds.com
Hypoxic-ischemic encephalopathy (HIE) is a severe central nervous system injury in
neonates secondary to perinatal asphyxia. It may cause devastating lifelong neurocognitive …

Neonatal encephalopathy: current management and future trends

EA Schump - Critical Care Nursing Clinics, 2018 - ccnursing.theclinics.com
Hypoxic ischemic encephalopathy (HIE) can have lifelong consequences for infants
suffering from it and their families. Most recent literature estimates neonatal deaths from HIE …

[HTML][HTML] A novel clinical risk scoring system for neurodevelopmental outcomes among survivors of neonatal hypoxic-ischemic encephalopathy (HIE)

T Estiphan, J Sturza, RA Shellhaas… - Pediatrics & Neonatology, 2023 - Elsevier
Objective We aimed to develop a risk scoring system as a predictor of 24-month
neurodevelopmental outcomes (cognitive, language, and motor) for neonates treated with …

Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy

S Shankaran, A Pappas, AR Laptook… - …, 2008 - publications.aap.org
BACKGROUND. Whole-body hypothermia reduced the frequency of death or
moderate/severe disabilities in neonates with hypoxic-ischemic encephalopathy in a …

Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop

RD Higgins, T Raju, AD Edwards, DV Azzopardi… - The Journal of …, 2011 - jpeds.com
Perinatal hypoxic-ischemic encephalopathy (HIE), a subset of neonatal encephalopathy, is
associated with high neonatal mortality and severe long-term neurologic morbidity. Until …

Short-term outcome and predictors of survival among neonates with moderate or severe hypoxic ischemic encephalopathy: data from the Indian Neonatal …

C Kumar, G Peruri, N Plakkal, TP Oleti, AS Aradhya… - Indian Pediatrics, 2022 - Springer
Background Among term and late preterm infants, hypoxic ischemic encephalopathy (HIE) is
an important cause of mortality, and neurologic morbidity among survivors. Objective The …

Implications of the HELIX trial for treating infants with hypoxic-ischaemic encephalopathy in low-to-middle-income countries

JO Davidson, MR Battin, AJ Gunn - … of Disease in Childhood-Fetal and …, 2023 - fn.bmj.com
Perinatal hypoxia-ischaemia (HI) is the single most common trigger of perinatal brain injury,
and contributes to over 2 million deaths worldwide each year, of which about 96% were from …