Icosalide is an unusual two-tailed lipocyclopeptide antibiotic that was originally isolated from
a fungal culture. Yet, its biosynthesis and ecological function have remained enigmatic. By …

Burkholderia is a multi-talented genus of Gram-negative bacteria, which in recent years has
become increasingly recognised as a promising source of bioactive natural products …

The class of cyclic lipopeptide natural products consists of compounds with a diverse range
of bioactivities. In this study, we elucidated the structure of the cyclic lipopeptide anikasin …

Investigating the ecological context of microbial predator–prey interactions enables the
identification of microorganisms, which produce multiple secondary metabolites to evade …

Pseudomonas species are metabolically robust, with capacity to produce secondary
metabolites including cyclic lipopeptides (CLPs). Herein we conducted a chemical analysis …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a
structurally diverse group of natural products. They feature a wide range of intriguing post …

Within the framework of our genome‐based program to discover new antibiotic lipopeptides
from Pseudomonads, brabantamides A–C were isolated from plant‐associated …

Modular biosynthetic machineries such as polyketide synthases (PKSs) or nonribosomal
peptide synthetases (NRPSs) give rise to a vast structural diversity of bioactive metabolites …

Xanthomonas albilineans causes leaf scald, a lethal disease of sugarcane. Compared to
other species of Xanthomonas, X. albilineans exhibits distinctive pathogenic mechanisms …

The rice seedling blight fungus Rhizopus microsporus weakens or kills plants by means of a
potent toxin produced by endobacteria (Burkholderia rhizoxinica) that live within the fungal …