Recent in vivo evidences of particle-based delivery of small-interfering RNA (siRNA) into solid tumors
Y Wen, WS Meng - Journal of pharmaceutical innovation, 2014 - Springer
Small-interfering RNA (siRNA) is both a powerful tool in research and a promising
therapeutic platform to modulate expression of disease-related genes. Malignant tumors are …
therapeutic platform to modulate expression of disease-related genes. Malignant tumors are …
Liposomal siRNA nanocarriers for cancer therapy
B Ozpolat, AK Sood, G Lopez-Berestein - Advanced drug delivery reviews, 2014 - Elsevier
Small interfering RNAs (siRNA) have recently emerged as a new class of therapeutics with a
great potential to revolutionize the treatment of cancer and other diseases. A specifically …
great potential to revolutionize the treatment of cancer and other diseases. A specifically …
Small delivery vehicles of siRNA for enhanced cancer targeting
Small interfering RNA (siRNA) drugs have been considered to treat various diseases in
major organs. However, siRNA drugs developed for cancer therapy are hindered from …
major organs. However, siRNA drugs developed for cancer therapy are hindered from …
Delivery of small interfering RNAs by nanovesicles for cancer therapy
S Pengnam, S Plianwong, B Yingyongnarongkul… - Drug Metabolism and …, 2022 - Elsevier
Small interfering ribonucleic acids (siRNAs) are originally recognized as an intermediate of
the RNA interference (RNAi) pathway. They can inhibit or silence various cellular pathways …
the RNA interference (RNAi) pathway. They can inhibit or silence various cellular pathways …
Recent progress in development of siRNA delivery vehicles for cancer therapy
Recent progress in RNA biology has broadened the scope of therapeutic targets of RNA
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …
drugs for cancer therapy. However, RNA drugs, typically small interfering RNAs (siRNAs) …
Nanomedicine based approaches for the delivery of siRNA in cancer
B Ozpolat, AK Sood… - Journal of internal …, 2010 - Wiley Online Library
Small interfering RNA (siRNA) technology holds great promise as a therapeutic intervention
for targeted gene silencing in cancer and other diseases. However, in vivo systemic delivery …
for targeted gene silencing in cancer and other diseases. However, in vivo systemic delivery …
[HTML][HTML] Nanoparticles as drug delivery systems in cancer medicine: emphasis on RNAi-containing nanoliposomes
MR Díaz, PE Vivas-Mejia - Pharmaceuticals, 2013 - mdpi.com
Nanomedicine is a growing research field dealing with the creation and manipulation of
materials at a nanometer scale for the better treatment, diagnosis and imaging of diseases …
materials at a nanometer scale for the better treatment, diagnosis and imaging of diseases …
[HTML][HTML] Nanoparticles-based strategies to improve the delivery of therapeutic small interfering RNA in precision oncology
J Huang, K Xiao - Pharmaceutics, 2022 - mdpi.com
Small interfering RNA (siRNA) can selectively suppress the expression of disease-causing
genes, holding great promise in the treatment of human diseases, including malignant …
genes, holding great promise in the treatment of human diseases, including malignant …
Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy
During recent decades there have been remarkable advances and profound changes in
cancer therapy. Many therapeutic strategies learned at the bench, including monoclonal …
cancer therapy. Many therapeutic strategies learned at the bench, including monoclonal …
Tumor‐targeting multifunctional nanoparticles for siRNA delivery: Recent advances in cancer therapy
RNA interference (RNAi) is a naturally occurring regulatory process that controls
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …
posttranscriptional gene expression. Small interfering RNA (siRNA), a common form of RNAi …