The potential prognostic and therapeutic application of tissue and circulating microRNAs in cervical cancer

M Hasanzadeh, M Movahedi, M Rejali… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer (CC) is a common malignancy in women and a major cause of cancer‐
related mortality globally. Some novel biomarkers may enable the early diagnosis and …

Altered microRNA expression associated with chromosomal changes contributes to cervical carcinogenesis

SM Wilting, PJF Snijders, W Verlaat, A Jaspers… - Oncogene, 2013 - nature.com
Little is known about the alterations in microRNA (miRNA) expression patterns during the
consecutive stages of cervical cancer development and their association with chromosomal …

[HTML][HTML] Identification of miRNAs in cervical mucus as a novel diagnostic marker for cervical neoplasia

S Kawai, T Fujii, I Kukimoto, H Yamada, N Yamamoto… - Scientific reports, 2018 - nature.com
Abstract microRNAs (miRNAs) play important roles in regulation of gene expression during
cervical carcinogenesis. We investigated expression profiles of miRNAs in cervical cancer …

Microarray profile of micro‐ribonucleic acid in tumor tissue from cervical squamous cell carcinoma without human papillomavirus

YL Zhang, Y Dai, YS Huang, L Ma, Y Yin… - Journal of Obstetrics …, 2009 - Wiley Online Library
Aims: Micro‐ribonucleic acid (miRNA) are noncoding RNA molecules of 21 to 24 nt that
regulate the expression of target genes in a post‐transcriptional manner. Evidence indicates …

A new microRNA expression signature for cervical cancer

P Sun, Y Shen, JM Gong, LL Zhou, JH Sheng… - International Journal of …, 2017 - ijgc.bmj.com
Background Cervical cancer is the second most common cancer among women worldwide.
The potential of microRNAs as novel biomarkers in cervical cancer is growing. Objectives In …

[HTML][HTML] Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth

X Wang, S Tang, SY Le, R Lu, JS Rader, C Meyers… - PloS one, 2008 - journals.plos.org
MicroRNAs (miRNAs) play important roles in cancer development. By cloning and
sequencing of a HPV16+ CaSki cell small RNA library, we isolated 174 miRNAs (including …

[HTML][HTML] Expression profile of circulating microRNAs as a promising fingerprint for cervical cancer diagnosis and monitoring

W Jia, Y Wu, Q Zhang, GE Gao… - Molecular and …, 2015 - spandidos-publications.com
Sensitive and specific biomarkers for the early detection of cervical cancer are urgently
required to reduce the high morbidity and mortality of this disease. We previously …

The roles and clinical significance of microRNAs in cervical cancer

F Wang, B Li, X Xie - 2016 - digitum.um.es
Cervical carcinogenesis induced by persistent human papillomavirus (HPV) infection
represents a stepwise progression from precursors to invasive cervical cancer. Accumulated …

MicroRNA miR-886-5p inhibits apoptosis by down-regulating Bax expression in human cervical carcinoma cells

JH Li, X Xiao, YN Zhang, YM Wang, LM Feng… - Gynecologic …, 2011 - Elsevier
OBJECTIVE: MicroRNA (miRNA) plays an essential role in the progression of a variety of
cancers, but its role in cervical cancer progression is not well defined. We aimed to test …

Oncogenic micro RNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer

SS Liu, KKL Chan, DKH Chu, TN Wei… - Molecular …, 2018 - Wiley Online Library
Cervical cancer is one of the leading causes of cancer death in women globally, despite the
widespread use of cytology/human papillomavirus (HPV) screening. In the present study, we …