[HTML][HTML] Withdrawal of unnecessary antidepressant medication: a randomised controlled trial in primary care

R Eveleigh, E Muskens, P Lucassen, P Verhaak… - BJGP open, 2018 - bjgpopen.org
Background Antidepressant use has increased exponentially in recent decades, mostly due
to long continuation. Aim To assess the effectiveness of a tailored recommendation to …

Prescribing ANtiDepressants Appropriately (PANDA): a cluster randomized controlled trial in primary care

E Muskens, R Eveleigh, P Lucassen, C van Weel… - BMC Family …, 2013 - Springer
Background Inappropriate use of antidepressants (AD), defined as either continuation in the
absence of a proper indication or continuation despite the lack of therapeutic efficacy …

'Never change a winning team': GPs' perspectives on discontinuation of long-term antidepressants

S Anthierens, ML van Driel, AD Sutter… - … Journal of Primary …, 2021 - Taylor & Francis
Background Long-term antidepressant use, much longer than recommended by guidelines,
can harm patients and generate unnecessary costs. Most antidepressants are prescribed by …

Should I, can I, dare I? Patients' view on stopping long-term antidepressant use, a qualitative study

E Van Leeuwen, S Anthierens, ML van Driel… - Acta Clinica …, 2022 - Taylor & Francis
Background and aim The rise in long-term antidepressant use is concerning. Long-term
antidepressant (AD) use, much longer than recommended by guidelines, can result in risk of …

Restarting antidepressant treatment following early discontinuation—a primary care database study

C Burton, AJ Cochran, IM Cameron - Family practice, 2015 - academic.oup.com
Background. Many patients in primary care stop antidepressant treatment after only one
prescription, so do not benefit from treatment. Some patients who stop initial antidepressant …

Patients' attitudes to discontinuing not-indicated long-term antidepressant use: barriers and facilitators

R Eveleigh, A Speckens, C van Weel… - Therapeutic …, 2019 - journals.sagepub.com
Background: Long-term antidepressant use has increased exponentially, though this is not
always according to guidelines. Our previous randomized controlled trial (RCT) showed that …

Long-term antidepressant use: a qualitative study on perspectives of patients and GPs in primary care

RC Bosman, KM Huijbregts, PFM Verhaak… - British Journal of …, 2016 - bjgp.org
Background Antidepressant use is often prolonged in patients with anxiety and/or
depressive disorder (s) compared with recommendations in treatment guidelines to …

[HTML][HTML] Maintenance or discontinuation of antidepressants in primary care

G Lewis, L Marston, L Duffy, N Freemantle… - … England Journal of …, 2021 - Mass Medical Soc
Background Patients with depression who are treated in primary care practices may receive
antidepressants for prolonged periods. Data are limited on the effects of maintaining or …

Why do patients discontinue antidepressant therapy early? A qualitative study

M Jaffray, AH Cardy, IC Reid… - The European journal of …, 2014 - Taylor & Francis
Background: Current guidelines for antidepressant prescribing are that treatment should be
continued following the resolution of symptoms: six months after a first episode and for at …

New users of antidepressant medications: first episode duration and predictors of discontinuation

CY Lu, E Roughead - European journal of clinical pharmacology, 2012 - Springer
Purpose Clinical guidelines recommend that antidepressant treatment should be continued
for at least 6 months. We examined persistence in patients initiated on an antidepressant …