Chemerin-9 stimulates migration in rat cardiac fibroblasts in vitro

A Yamamoto, A Sagara, K Otani, M Okada… - European Journal of …, 2021 - Elsevier
Since chemerin is an adipocytokine whose concentration in blood increases in the subjects
with various cardiac diseases, chemerin may be involved in pathogenesis of cardiac …

[HTML][HTML] The adipokine chemerin induces apoptosis in cardiomyocytes

D Rodríguez-Penas, S Feijóo-Bandín… - Cellular Physiology and …, 2015 - karger.com
Background: The adipokine chemerin has been associated with cardiovascular disease. We
investigated the effects of chemerin on viability and intracellular signalling in murine …

Chemerin induces insulin resistance in rat cardiomyocytes in part through the ERK1/2 signaling pathway

R Zhang, S Liu, B Guo, L Chang, Y Li - Pharmacology, 2015 - karger.com
Aims: Chemerin is a novel adipokine that is closely associated with cardiovascular diseases
and glucose homeostasis. This study aimed to investigate the effects of chemerin on insulin …

Chemerin promotes the proliferation and migration of vascular smooth muscle and increases mouse blood pressure

H Kunimoto, K Kazama, M Takai… - American Journal …, 2015 - journals.physiology.org
Blood chemerin concentration shows positive correlation not only with body mass index and
serum triglyceride level but also with systolic blood pressure. While it seems likely that …

Chemerin regulates crosstalk between adipocytes and vascular cells through Nox

KB Neves, A Nguyen Dinh Cat, RAM Lopes, FJ Rios… - …, 2015 - Am Heart Assoc
Adipocytes produce adipokines, including chemerin, a chemoattractant that mediates effects
through its ChemR23 receptor. Chemerin has been linked to endothelial dysfunction and …

Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells

H Sell, J Laurencikiene, A Taube, K Eckardt… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Chemerin is an adipokine that affects adipogenesis and glucose homeostasis
in adipocytes and increases with BMI in humans. This study was aimed at investigating the …

Chemerin-9, a potent agonist of chemerin receptor (ChemR23), prevents atherogenesis

K Sato, H Yoshizawa, T Seki, R Shirai… - Clinical …, 2019 - portlandpress.com
Plasma levels of chemerin, an adipocytokine produced from the adipose tissues and liver,
are associated with metabolic syndrome and coronary artery disease (CAD). Chemerin and …

[HTML][HTML] The effect of chemerin on cardiac parameters and gene expressions in isolated perfused rat heart

Ö Kutlay, Z Kaygısız, B Kaygısız - Balkan Medical Journal, 2019 - ncbi.nlm.nih.gov
Background: Chemerin is a novel chemoattractant adipokine expressed in cardiovascular
system, and its receptor has been detected in the epicardial adipose tissue. Aims: To …

Chemerin-9-induced contraction was enhanced through the upregulation of smooth muscle chemokine-like receptor 1 in isolated pulmonary artery of pulmonary …

A Omori, M Goshima, C Kakuda, T Kodama… - … -European Journal of …, 2020 - Springer
Chemerin is an adipocytokine having cardiovascular effects. Chemokine-like receptor 1
(CMKLR1) and chemokine (CC motif) receptor-like 2 (CCRL2) are chemerin receptors …

Chemerin-induced arterial contraction is Gi-and calcium-dependent

DJ Ferland, ES Darios, RR Neubig, B Sjögren… - Vascular …, 2017 - Elsevier
Chemerin is an adipokine associated with increased blood pressure, and may link obesity
with hypertension. We tested the hypothesis that chemerin-induced contraction of the …