Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic pressure Overload–induced Cardiac Hypertrophy and …

Y Ye, H Gong, X Wang, J Wu, S Wang… - Journal of …, 2015 - journals.lww.com
We previously showed that Qiliqiangxin (QL) capsules could ameliorate cardiac hypertrophy
and remodeling in a mouse model of pressure overload. Here, we compared the effects of …

Qiliqiangxin inhibits the development of cardiac hypertrophy, remodeling, and dysfunction during 4 weeks of pressure overload in mice

Y Zou, L Lin, Y Ye, J Wei, N Zhou, Y Liang… - Journal of …, 2012 - journals.lww.com
Qiliqiangxin (QL), a traditional Chinese medicine, has been used in the treatment of chronic
heart failure. However, whether QL can benefit cardiac remodeling in the hypertensive state …

[HTML][HTML] Traditional Chinese medication Qiliqiangxin protects against cardiac remodeling and dysfunction in spontaneously hypertensive rats

H Wang, X Zhang, P Yu, Q Zhou, J Zhang… - … Journal of Medical …, 2017 - ncbi.nlm.nih.gov
Qiliqiangxin (QLQX), a traditional Chinese herbs medication, exerted protective effect in
chronic heart failure patients in a multicenter randomized double-blind study. QLQX has also …

Qiliqiangxin improves cardiac function in spontaneously hypertensive rats through the inhibition of cardiac chymase

W Liu, J Chen, T Xu, W Tian, Y Li… - American Journal of …, 2012 - academic.oup.com
Background: This study was designed to investigate the effects and mechanism of action of
the traditional Chinese drug formula, qiliqiangxin (QLQX), on cardiac function in …

[HTML][HTML] Qiliqiangxin attenuates phenylephrine-induced cardiac hypertrophy through downregulation of MiR-199a-5p

H Zhang, S Li, Q Zhou, Q Sun, S Shen, Y Zhou… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Qiliqiangxin (QL), a traditional Chinese medicine, has long been used to
treat chronic heart failure. Previous studies demonstrated that QL could prevent cardiac …

[HTML][HTML] Qiliqiangxin improves cardiac function and attenuates cardiac remodeling in rats with experimental myocardial infarction

J Wang, J Zhou, X Ding, L Zhu, K Jiang… - … Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Objective: It has been reported that Qiliqiangxin (QL), a traditional Chinese medicine
compound, could inhibit cardiac hypertrophy and remodeling, and improve cardiac function …

[HTML][HTML] Qiliqiangxin attenuates isoproterenol-induced cardiac remodeling in mice

J Zhang, M Huang, S Shen, X Wu, X Wu… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Background: To further explore the role of PPARγ in QL treatment, ISO-induced mice model
and following methods were established. Methods: Cardiac remodeling on mice model was …

Traditional Chinese Medication Qiliqiangxin attenuates cardiac remodeling after acute myocardial infarction in mice

L Tao, S Shen, S Fu, H Fang, X Wang, S Das… - Scientific Reports, 2015 - nature.com
In a multicenter randomized double-blind study we demonstrated that Qiliqiangxin (QLQX), a
traditional Chinese medicine, had a protective effect in heart failure patients. However …

[HTML][HTML] Qiliqiangxin prevents right ventricular remodeling by inhibiting apoptosis and improving metabolism reprogramming with pulmonary arterial hypertension

Y Lu, J Wu, Y Sun, L Xin, Z Jiang, H Lin… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Pathological remodeling of the right ventricular (RV) contributes to the mortality of pulmonary
arterial hypertension (PAH) patients, and RV myocardial apoptosis and metabolism play …

[HTML][HTML] Qiliqiangxin protects against cardiac ischemia-reperfusion injury via activation of the mTOR pathway

Y Zhou, H Fang, S Lin, S Shen, L Tao, J Xiao… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Qiliqiangxin (QL) has been used for the treatment of chronic heart failure
in China. Accumulating evidence suggests QL's cardio-protective effects on continuous …