An in situ extraction and derivatization method for rapid analysis of short-chain fatty acids in rat fecal samples by gas chromatography tandem mass spectrometry

NH Park, MS Kim, W Lee, ME Lee, J Hong - Analytical Methods, 2017 - pubs.rsc.org
Short-chain fatty acids (SCFAs) are major products of gut microbial fermentation and
changes in their levels in a biological system reflect the progress of various diseases …

Simultaneous quantification of eleven short-chain fatty acids by derivatization and solid phase microextraction-gas chromatography tandem mass spectrometry

Z Fu, Q Jia, H Zhang, L Kang, X Sun, M Zhang… - … of Chromatography A, 2022 - Elsevier
As metabolites of the gut microbiome, short-chain fatty acids (SCFAs) played an important
role in the diagnosis of the metabolic diseases. Because of the high polarity, high volatility …

Rapid and accurate simultaneous determination of seven short-chain fatty acids in feces by gas chromatography–mass spectrometry (GC-MS): application in type 2 …

H Wang, Y Liu, J Shao, Y Luo, W Cai, L Chen - Analytical Letters, 2020 - Taylor & Francis
Short-chain fatty acids (SCFAs) are carboxylic acids that contain fewer than six carbons and
are the metabolites of the intestinal flora. SCFAs participate in almost all circulatory system …

An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography–tandem mass spectrometry

J Han, K Lin, C Sequeira, CH Borchers - Analytica chimica acta, 2015 - Elsevier
Short-chain fatty acids (SCFAs) are produced by anaerobic gut microbiota in the large
bowel. Qualitative and quantitative measurements of SCFAs in the intestinal tract and the …

A rapid and convenient derivatization method for quantitation of short‐chain fatty acids in human feces by ultra‐performance liquid chromatography/tandem mass …

H Fu, Q Zhang, X Huang, Z Ma, X Zheng… - Rapid …, 2020 - Wiley Online Library
Rationale Short‐chain fatty acids (SCFAs) are associated with intestinal microbiota and
diseases in humans. SCFAs have a low response in mass spectrometry, and in order to …

A sensitive GC/MS detection method for analyzing microbial metabolites short chain fatty acids in fecal and serum samples

S Zhang, H Wang, MJ Zhu - Talanta, 2019 - Elsevier
Gut microbiota and their major metabolites, short-chain fatty acids (SCFAs), are recognized
as important players in gut homeostasis and metabolic disease occurance. A convenient …

Accurate and reliable quantitation of short chain fatty acids from human feces by ultra high-performance liquid chromatography-high resolution mass spectrometry …

L Chen, X Sun, AS Khalsa, MT Bailey… - … of pharmaceutical and …, 2021 - Elsevier
Short chain fatty acids (SCFAs), generated from microbial fermentation of dietary fibers, can
regulate weight, appetite and energy homeostasis. Therefore, measuring SCFAs in fecal …

Optimization and validation of direct gas chromatography-mass spectrometry method for simultaneous quantification of ten short-chain fatty acids in rat feces

JH Zhu, Q Mao, SY Wang, H Liu, SS Zhou… - … of Chromatography A, 2022 - Elsevier
Short-chain fatty acids (SCFAs) play key roles in maintaining health and treating disease.
Quantification of important fecal SCFAs is necessary to facilitate the clarification of their …

Enhanced detection of short‐chain fatty acids using gas chromatography mass spectrometry

H Gu, P Jasbi, J Patterson, Y Jin - Current protocols, 2021 - Wiley Online Library
Short‐chain fatty acids (SCFAs) are produced mainly by intestinal microbiota and play an
important role in many host biological processes such as immune system development …

Fast quantification of short‐chain fatty acids in rat plasma by gas chromatography

CY Wang, YW Chen, YL Tain, SKC Chang… - Journal of food …, 2020 - Wiley Online Library
Short‐chain fatty acids (SCFAs) are the main metabolites of the intestinal flora and play an
important role in the interaction between the intestinal flora and host metabolism. Therefore …