Antiplatelet, anticoagulant or both? A tool for pharmacists

A Schmode, M Ackman… - … Journal/Revue des …, 2019 - journals.sagepub.com
Patients with atrial fibrillation (AF) are at an increased risk for thrombosis, and anticoagulant
therapy, preferably with a direct oral anticoagulant (DOAC) for most patients, is indicated for …

Treating patients with anticoagulants and antiplatelet drugs is always a balance between risk for thrombosis vs. risk for bleeding

S Agewall - European Heart Journal-Cardiovascular …, 2022 - academic.oup.com
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated
with an increased risk of cardioembolic stroke. Oral anticoagulation reduces the risk of …

[HTML][HTML] Bleeding in patients with atrial fibrillation treated with combined antiplatelet and anticoagulant therapy: time to turn the corner

K Xu, NC Chan - Annals of Translational Medicine, 2019 - ncbi.nlm.nih.gov
Anticoagulation is the mainstay for stroke prevention in patients with atrial fibrillation (AF).
Many patients with AF also have a concomitant indication for either single or dual …

Antithrombotic therapy in atrial fibrillation: stop triple therapy and start optimizing dual therapy?

B Wernly, M Lichtenauer, D Erlinge, C Jung - Clinical Research in …, 2020 - Springer
Based on recent studies, we want to provoke thoughts on how to further optimize research
on antiplatelet treatment in patients on oral anticoagulation (OAC). One in three patients …

Management of antiplatelet and anticoagulant therapy in patients with atrial fibrillation in the setting of acute coronary syndromes or percutaneous coronary …

D Capodanno, DJ Angiolillo - Circulation: Cardiovascular …, 2014 - Am Heart Assoc
In patients with AF, adjusted-dose warfarin and antiplatelet agents reduce the risk for stroke
by≈ 65% and by≈ 20%, respectively. 17 However, oral antiplatelet agents do not perform …

Patients With Atrial Fibrillation and PCI or ACS: Does Predicted Risk Matter?

P Vranckx, DJ Angiolillo, M Valgimigli - Journal of the American College of …, 2022 - jacc.org
Approximately, 1 in 5 patients with atrial fibrillation (AF) will undergo percutaneous coronary
intervention (PCI) or experience an acute coronary syndrome (ACS). In light of their …

Antithrombotics: from aspirin to DOACs in coronary artery disease and atrial fibrillation (Part 3/5)

FWA Verheugt, JM Ten Berg, RF Storey… - Journal of the American …, 2019 - jacc.org
For secondary prevention of coronary artery disease (CAD), oral antiplatelet therapy is
essential. In case of coronary intervention, temporary dual antiplatelet therapy is mandatory …

Combined antiplatelet therapy and oral anticoagulation: Is a balance between thromboembolism and bleeding possible?

N Kuzniatsova, GYH Lip - International …, 2011 - internationaljournalofcardiology.com
Chronic oral anticoagulation (OAC) treatment is mandatory in patients with mechanical heart
valves, the majority of the patients with atrial fibrillation (AF), patients with deep venous …

Concomitant use of antiplatelets and anticoagulants in patients with coronary heart disease and atrial fibrillation: what do recent clinical trials teach us?

DH Lam, SM Bell, RS Hira - Current atherosclerosis reports, 2018 - Springer
Abstract Purpose of Review Coronary heart disease (CHD) and atrial fibrillation (AF) are
among the most common cardiovascular diseases. A significant proportion of patients have …

Concomitant Use of Single Antiplatelet Therapy With Edoxaban or Warfarin in Patients With Atrial Fibrillation: Analysis From the ENGAGE AF‐TIMI 48 Trial

H Xu, CT Ruff, RP Giugliano, SA Murphy… - Journal of the …, 2016 - Am Heart Assoc
Background We studied the concomitant use of single antiplatelet therapy (SAPT) on the
efficacy and safety of the anti‐Xa agent edoxaban in patients with atrial fibrillation (AF) …