Tissue engineering from human mesenchymal amniocytes: a prelude to clinical trials

SM Kunisaki, M Armant, GS Kao, K Stevenson… - Journal of pediatric …, 2007 - Elsevier
PURPOSE: The surgical treatment of congenital anomalies using tissues engineered from
amniotic fluid-derived mesenchymal cells has been validated experimentally. As a …

The amniotic fluid as a source of cells for fetal tissue engineering

A Kaviani, TE Perry, A Dzakovic, RW Jennings… - Journal of pediatric …, 2001 - Elsevier
Purpose: This study was aimed at determining whether fetal tissue constructs can be
engineered from cells normally found in the amniotic fluid. Methods: A subpopulation of …

Preclinical regulatory validation of a 3-stage amniotic mesenchymal stem cell manufacturing protocol

SA Steigman, M Armant, L Bayer-Zwirello… - Journal of Pediatric …, 2008 - Elsevier
PURPOSE: Because of the 4 to 6-month interval between a diagnostic amniocentesis and
birth, clinical application of amniotic mesenchymal stem cell (AMSC)-based therapies …

Fetal tissue engineering from amniotic fluid

A Kaviani, K Guleserian, RW Jennings… - Journal of the American …, 2003 - Elsevier
BACKGROUND: We have recently shown, in an animal model, that amniotic fluid can be a
source of cells for fetal tissue engineering. This study was aimed at determining whether …

Term amniotic fluid: an unexploited reserve of mesenchymal stromal cells for reprogramming and potential cell therapy applications

R Moraghebi, A Kirkeby, P Chaves, RE Rönn… - Stem Cell Research & …, 2017 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) are currently being evaluated in
numerous pre-clinical and clinical cell-based therapy studies. Furthermore, there is an …

Congenital anomalies: treatment options based on amniotic fluid-derived stem cells

SM Kunisaki - Organogenesis, 2012 - Taylor & Francis
Over the past decade, amniotic fluid-derived stem cells have emerged as a novel,
experimental approach for the treatment of a wide variety of congenital anomalies …

Routine clonal expansion of mesenchymal stem cells derived from amniotic fluid for perinatal applications

S Zia, J Toelen, M Mori da Cunha… - Prenatal …, 2013 - Wiley Online Library
ABSTRACT Introduction Stem cells (SCs) isolated from amniotic fluid (AF) are a promising
source for autologous perinatal cell therapy. The aim of this study was to develop a routine …

The placenta as a cell source in fetal tissue engineering

A Kaviani, TE Perry, CM Barnes, JT Oh… - Journal of pediatric …, 2002 - Elsevier
Purpose: This study was aimed at determining whether fetal tissue constructs can be
engineered from cells derived from the placenta. Methods: A subpopulation of …

Fetal cartilage engineering from amniotic mesenchymal progenitor cells

SM Kunisaki, RW Jennings… - Stem cells and …, 2006 - liebertpub.com
We determined whether cartilage could be engineered from mesenchymal progenitor cells
(MPCs) normally found in amniotic fluid. Mesenchymal amniocytes were isolated from ovine …

Amniotic fluid as a rich source of mesenchymal stromal cells for transplantation therapy

I Antonucci, L Stuppia, Y Kaneko, S Yu… - Cell …, 2011 - journals.sagepub.com
Stem cells isolated from amniotic fluid are known to be able to differentiate into different cells
types, thus being considered as a powerful tool for cellular therapy of different human …