Abstract Interleukin 10 (IL-10), a cytokine with inhibitory activity on inflammation and cell-
mediated immune responses, holds enormous potential for the treatment of inflammatory …

Interleukin-10 is the most potent anti-inflammatory cytokine yet identified. It has multiple
actions affecting the innate immune system as well as humoral and cellular immune …

Abstract Human interleukin-10 (IL-10) is a potent anti-inflammatory cytokine that inhibits the
synthesis of the major proinflammatory cytokines and chemokines. IL-10 is the principal TH2 …

Abstract Interleukin (IL)-10 is a pleiotropic cytokine produced by both T cells and
macrophages and possesses both anti-inflammatory and immunosuppressive properties. IL …

Interleukin‐10 (IL‐10) has long been recognized to have potent and broad‐spectrum anti‐
inflammatory activity, which has been unequivocally established in various models of …

IL-10 is an anti-inflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK
cells, and macrophages, all of which are required for optimal pathogen clearance but also …

Interleukin 10 (IL-10) indirectly prevents antigen-specific T-cell activation, which is
associated with downregulation of the antigen presentation and accessory cell functions of …

The IL-10 family of cytokines consists of nine members: IL-10, IL-19, IL-20, IL-22, IL-24, IL-
26, and the more distantly related IL-28A, IL-28B, and IL-29. Evolutionarily, IL-10 family …

The presented information reflects a state-of-the-art summary of the pleiotropic effects of IL-
10 in vitro and in vivo and will contribute to our understanding of the role of ILj-10 in the …

Abstract Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central
role in infection by limiting the immune response to pathogens and thereby preventing …