STUDY QUESTION Does testosterone use in females affect reproductive potential,
particularly with regard to the production of fertilizable gametes? SUMMARY ANSWER …

Studies show that a subset of transgender men desire children; however, there is a paucity
of literature on the effect of gender-affirming testosterone therapy on reproductive function. In …

STUDY QUESTION Can mice serve as a translational model to investigate the reproductive
effects of testosterone (T) therapy commonly used by transgender men? SUMMARY …

More adolescents are coming out as transgender each year and are put on puberty blockers
to suppress natal puberty, which is then followed by cross-hormone treatment to achieve …

Purpose To compare assisted reproductive technology (ART) outcomes among transgender
men with those of fertile cisgender women. Methods This retrospective cohort study included …

Background The impact of gender-affirming testosterone on fertility is poorly understood,
with ovarian histopathologic studies showing variable results, some with a detrimental effect …

Some transmasculine individuals may be interested in pausing gender-affirming
testosterone therapy and carrying a pregnancy. The ovarian impact of taking and pausing …

STUDY QUESTION Can mice serve as a translational model to examine the reproductive
consequences of pubertal suppression with GnRH agonist (GnRHa) followed by …

Objective To establish if the cessation of testosterone (T) therapy reverses T-induced
acyclicity in a transgender mouse model that allows for well-defined T cessation timing …

Transgender and nonbinary people with female birth sex may utilize testosterone therapy for
masculinization. Individuals interested in reproduction using their own gametes should be …