Increased energy consumption coupled with depleting petroleum reserves and increased
greenhouse gas emissions have renewed our interest in generating fuels from renewable …

Highlights•Microbial cell factories can be tailored for producing certain 'drop-in'chemicals.•
Metabolic engineering has greatly enhanced the development of microbial cell …

Lignocellulose is the most abundant biomass on earth with an annual production of about
2× 10 11 tons. It is an inedible renewable carbonaceous resource that is very rich in pentose …

Background Lignocellulosic biomass is a promising renewable feedstock for biofuel
production. Acetate is one of the major inhibitors liberated from hemicelluloses during …

Understanding the complex interactions that occur between heterologous and native
biochemical pathways represents a major challenge in metabolic engineering and synthetic …

Integration of the analytical framework and experimental tools of metabolic engineering with
emerging technologies such as DNA microarrays and directed evolution stands to …

The advent of various systems metabolic engineering tools and strategies has enabled more
sophisticated engineering of microorganisms for the production of industrially useful fuels …

Increasing global energy demand and environmental concerns associated with petroleum
have raised interest in biofuels for reducing dependency on crude oil and promote carbon …

Background Zymomonas mobilis is a natural ethanologen being developed and deployed
as an industrial biofuel producer. To date, eight Z. mobilis strains have been completely …

Systems metabolic engineering, which recently emerged as metabolic engineering
integrated with systems biology, synthetic biology, and evolutionary engineering, allows …