Objective: We sought to evaluate the time to antibiotics for emergency department (ED)
patients meeting criteria for severe sepsis before and after the implementation of an ED …

Abstract Introduction The Severe Sepsis and Septic Shock Early Management Bundle (SEP-
1) identifies patients with “severe sepsis” and mandates antibiotics within a specific time …

Rationale. The impact of emergency department length of stay (EDLOS) upon sepsis
outcomes needs clarification. We sought to better understand the relationship between …

Importance There is uncertainty about whether prolonged infusions of β-lactam antibiotics
improve clinically important outcomes in critically ill adults with sepsis or septic shock …

PURPOSES: International guidelines recommend antibiotics within 1 hour of septic shock
recognition; however, a recently proposed performance measure is focused on measuring …

Recent literature has highlighted the importance of early identification and treatment of
sepsis; however, limited data exists to help recognize sepsis in the emergency department …

OBJECTIVES: Results of pre-post intervention studies of sepsis early warning systems have
been mixed, and randomized clinical trials showing efficacy in the emergency department …

Study objective Debate exists about the mortality benefit of administering antibiotics within
either 1 or 3 hours of sepsis onset. We performed this meta-analysis to analyze the effect of …

Abstract Background and Aims Some studies have suggested that earlier initiation of
antibiotics has shown positive outcomes in sepsis patients. We aimed to do a systematic …

Objetivo Evaluar cómo influye el retraso en la administración de la primera dosis de
antibiótico y la inadecuación de la pauta seleccionada en la supervivencia de los pacientes …