Allelic variation at alcohol metabolism genes (ADH1B, ADH1C, ALDH2) and alcohol dependence in an American Indian population
CJ Mulligan, RW Robin, MV Osier, N Sambuughin… - Human genetics, 2003 - Springer
Enzymes encoded by two gene families, alcohol dehydrogenase (ADH) and aldehyde
dehydrogenase (ALDH), mediate alcohol metabolism in humans. Allelic variants have been …
dehydrogenase (ALDH), mediate alcohol metabolism in humans. Allelic variants have been …
[HTML][HTML] The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants
HJ Edenberg - Alcohol Research & Health, 2007 - ncbi.nlm.nih.gov
The primary enzymes involved in alcohol metabolism are alcohol dehydrogenase (ADH)
and aldehyde dehydrogenase (ALDH). Both enzymes occur in several forms that are …
and aldehyde dehydrogenase (ALDH). Both enzymes occur in several forms that are …
[HTML][HTML] Biology, genetics, and environment: underlying factors influencing alcohol metabolism
Gene variants encoding several of the alcohol-metabolizing enzymes, alcohol
dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), are among the largest …
dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), are among the largest …
[HTML][HTML] Health-related effects of genetic variations of alcohol-metabolizing enzymes in African Americans
DM Scott, RE Taylor - Alcohol research & health, 2007 - ncbi.nlm.nih.gov
Alcohol metabolism involves two key enzymes—alcohol dehydrogenase (ADH) and
aldehyde dehydrogenase (ALDH). There are several types of ADH and ALDH, each of …
aldehyde dehydrogenase (ALDH). There are several types of ADH and ALDH, each of …
Haplotype‐based study of the association of alcohol‐metabolizing genes with alcohol dependence in four independent populations
Background: Ethanol is metabolized by 2 rate‐limiting reactions: alcohol dehydrogenases
(ADH) convert ethanol to acetaldehyde that is subsequently metabolized to acetate by …
(ADH) convert ethanol to acetaldehyde that is subsequently metabolized to acetate by …
Effect of the allelic variants of aldehyde dehydrogenase ALDH2*2 and alcohol dehydrogenase ADH1B*2on blood acetaldehyde concentrations
GS Peng, SJ Yin - Human genomics, 2009 - Springer
Alcoholism is a complex behavioural disorder. Molecular genetics studies have identified
numerous candidate genes associated with alcoholism. It is crucial to verify the disease …
numerous candidate genes associated with alcoholism. It is crucial to verify the disease …
[HTML][HTML] ALDH2, ADH1B, and ADH1C genotypes in Asians: a literature review
Variants of three genes encoding alcohol-metabolizing enzymes, the aldehyde
dehydrogenase gene ALDH2 and the alcohol dehydrogenase genes ADH1B and ADH1C …
dehydrogenase gene ALDH2 and the alcohol dehydrogenase genes ADH1B and ADH1C …
Genetic associations of alcohol and aldehyde dehydrogenase with alcohol dependence and their mechanisms of action
TL Wall - Therapeutic Drug Monitoring, 2005 - journals.lww.com
Two alcohol dehydrogenase genes (ADH1B and ADH1C on chromosome 4) and one
aldehyde dehydrogenase gene (ALDH2 on chromosome 12) exhibit functional …
aldehyde dehydrogenase gene (ALDH2 on chromosome 12) exhibit functional …
ADH and ALDH polymorphisms and alcohol dependence in Mexican and Native Americans
Background: Ethanol is primarily metabolized in the liver by two rate-limiting reactions:
conversion of ethanol to acetaldehyde by alcohol dehydrogenase (ADH) and subsequent …
conversion of ethanol to acetaldehyde by alcohol dehydrogenase (ADH) and subsequent …
Association of alcohol dehydrogenase genes with alcohol‐related phenotypes in a Native American community sample
IR Gizer, HJ Edenberg, DA Gilder… - Alcoholism: Clinical …, 2011 - Wiley Online Library
Background: Previous linkage studies, including a study of the Native American population
described in the present report, have provided evidence for linkage of alcohol dependence …
described in the present report, have provided evidence for linkage of alcohol dependence …