[PDF][PDF] The biophysics of lymphatic transport: engineering tools and immunological consequences

MJ O'Melia, AW Lund, SN Thomas - Iscience, 2019 - cell.com
Lymphatic vessels mediate fluid flows that affect antigen distribution and delivery, lymph
node stromal remodeling, and cell-cell interactions, to thus regulate immune activation. Here …

Implications of lymphatic transport to lymph nodes in immunity and immunotherapy

SN Thomas, NA Rohner… - Annual review of …, 2016 - annualreviews.org
Adaptive immune response consists of many highly regulated, multistep cascades that
protect against infection while preserving the health of autologous tissue. The proper …

Lymphatic vessels and their surroundings: how local physical factors affect lymph flow

E Solari, C Marcozzi, D Negrini, A Moriondo - Biology, 2020 - mdpi.com
Simple Summary Lymphatic vessels are responsible for the drainage of liquids, solutes, and
cells from interstitial spaces and serosal cavities. Their task is fundamental in order to avoid …

Modeling lymph flow and fluid exchange with blood vessels in lymph nodes

M Jafarnejad, MC Woodruff, DC Zawieja… - … research and biology, 2015 - liebertpub.com
Abstract Background: Lymph nodes (LNs) are positioned strategically throughout the body
as critical mediators of lymph filtration and immune response. Lymph carries cytokines …

Biomechanical control of lymphatic vessel physiology and functions

V Angeli, HY Lim - Cellular & Molecular Immunology, 2023 - nature.com
The ever-growing research on lymphatic biology has clearly identified lymphatic vessels as
key players that maintain human health through their functional roles in tissue fluid …

Lymphatic vessels in health and disease

CT Kesler, S Liao, LL Munn… - … : Systems Biology and …, 2013 - Wiley Online Library
The lymphatic vasculature plays vital roles in tissue fluid balance, immune defense,
metabolism, and cancer metastasis. In adults, lymphatic vessel formation and remodeling …

Afferent lymphatic transport and peripheral tissue immunity

MM Steele, AW Lund - The Journal of Immunology, 2021 - journals.aai.org
Lymphatic vessels provide an anatomical framework for immune surveillance and adaptive
immune responses. Although appreciated as the route for Ag and dendritic cell transport …

The lymphatic system in disease processes and cancer progression

TP Padera, EFJ Meijer, LL Munn - Annual review of biomedical …, 2016 - annualreviews.org
Advances in our understanding of the structure and function of the lymphatic system have
made it possible to identify its role in a variety of disease processes. Because it is involved …

Mechanobiology of lymphatic contractions

LL Munn - Seminars in cell & developmental biology, 2015 - Elsevier
The lymphatic system is responsible for controlling tissue fluid pressure by facilitating flow of
lymph (ie the plasma and cells that enter the lymphatic system). Because lymph contains …

[HTML][HTML] Method for the quantitative measurement of collecting lymphatic vessel contraction in mice

S Liao, D Jones, G Cheng… - Journal of biological …, 2014 - ncbi.nlm.nih.gov
Collecting lymphatic vessels are critical for the transport of lymph and its cellular contents to
lymph nodes for both immune surveillance and the maintenance of tissue-fluid balance …