[HTML][HTML] Five-gene signature associating with Gleason score serve as novel biomarkers for identifying early recurring events and contributing to early diagnosis for …

L Zhang, Y Li, X Wang, Y Ping, D Wang, Y Cao… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Compared to non-recurrent type, recurrent prostate adenocarcinoma (PCa) is
highly fatal, and significantly shortens the survival time of affected patients. Early and …

[HTML][HTML] The Development of a Gleason Score-Related Gene Signature for Predicting the Prognosis of Prostate Cancer

Y Yimamu, X Yang, J Chen, C Luo, W Xiao… - Journal of Clinical …, 2022 - mdpi.com
The recurrence of prostate cancer (PCa) is intrinsically linked to increased mortality. The
goal of this study was to develop an efficient and reliable prognosis prediction signature for …

[HTML][HTML] A Gleason score-related outcome model for human prostate cancer: a comprehensive study based on weighted gene co-expression network analysis

Y Wang, Z Yang - Cancer cell international, 2020 - Springer
Abstract Background Prostate cancer (PCa) is the second leading cause of cancer death in
men in 2018. Thus, the evaluation of prognosis is crucial for clinical treatment decision of …

[HTML][HTML] Gene expression analysis reveals a 5-gene signature for progression-free survival in prostate cancer

Z Mou, J Spencer, B Knight, J John, P McCullagh… - Frontiers in …, 2022 - frontiersin.org
Prostate cancer (PCa) is the second most common male cancer worldwide but effective
biomarkers for the presence or progression-risk of disease are currently elusive. We carried …

[HTML][HTML] Gene expression signature of Gleason score is associated with prostate cancer outcomes in a radical prostatectomy cohort

MA Jhun, MS Geybels, JL Wright, S Kolb, C April… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is a leading cause of cancer-related mortality worldwide. Gleason
score (GS) is one of the best predictors of PCa aggressiveness, but additional tumor …

Use of two gene panels for prostate cancer diagnosis and patient risk stratification

K Xiao, J Guo, X Zhang, X Feng, H Zhang, Z Cheng… - Tumor Biology, 2016 - Springer
Currently, no ideal prostate cancer (PCa) diagnostic or prognostic test is available due to the
lack of biomarkers with high sensitivity and specificity. There is an unmet medical need to …

[HTML][HTML] An accurate prostate cancer prognosticator using a seven-gene signature plus Gleason score and taking cell type heterogeneity into account

X Chen, S Xu, M McClelland, F Rahmatpanah… - 2012 - journals.plos.org
One of the major challenges in the development of prostate cancer prognostic biomarkers is
the cellular heterogeneity in tissue samples. We developed an objective Cluster-Correlation …

A four‐gene signature associated with clinical features can better predict prognosis in prostate cancer

P Yuan, L Ling, Q Fan, X Gao, T Sun, J Miao… - Cancer …, 2020 - Wiley Online Library
Prostate cancer (PCa) is one of the most deadly urinary tumors in men globally, and the 5‐
year over survival is poor due to metastasis of tumor. It is significant to explore potential …

[HTML][HTML] An expression signature at diagnosis to estimate prostate cancer patients' overall survival

Z Peng, L Skoog, H Hellborg, G Jonstam… - Prostate cancer and …, 2014 - nature.com
Background: This study aimed to identify biomarkers for estimating the overall and prostate
cancer (PCa)-specific survival in PCa patients at diagnosis. Methods: To explore the …

[HTML][HTML] Identification of potential key genes for pathogenesis and prognosis in prostate cancer by integrated analysis of gene expression profiles and the cancer …

S Liu, W Wang, Y Zhao, K Liang, Y Huang - Frontiers in oncology, 2020 - frontiersin.org
Background: Prostate cancer (PCa) is a malignancy of the urinary system with a high
incidence, which is the second most common male cancer in the world. There are still huge …