Neuromyelitis optica should be classified as an astrocytopathic disease rather than a demyelinating disease

K Fujihara, T Misu, I Nakashima… - Clinical and …, 2012 - Wiley Online Library
Neuromyelitis optica (NMO) is characterized by severe optic neuritis and transverse myelitis.
The relationship of NMO to multiple sclerosis (MS) has long been debated, but NMO has …

Neuromyelitis optica and astrocytic damage in its pathogenesis

K Fujihara - Journal of the neurological sciences, 2011 - Elsevier
Neuromyelitis optica (NMO) is characterized by severe optic neuritis and longitudinally
extended, transverse myelitis. There have been long controversial whether NMO is a variant …

Mechanisms of disease: aquaporin-4 antibodies in neuromyelitis optica

S Jarius, F Paul, D Franciotta, P Waters… - Nature clinical practice …, 2008 - nature.com
Neuromyelitis optica (NMO) is a rare CNS inflammatory disorder that predominantly affects
the optic nerves and spinal cord. Recent serological findings strongly suggest that NMO is a …

Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosis

T Misu, K Fujihara, A Kakita, H Konno, M Nakamura… - Brain, 2007 - academic.oup.com
Neuromyelitis optica (NMO) is an inflammatory and necrotizing disease clinically
characterized by selective involvement of the optic nerves and spinal cord. There has been …

[HTML][HTML] New insights into neuromyelitis optica

W Kim, SH Kim, HJ Kim - Journal of Clinical Neurology, 2011 - synapse.koreamed.org
Neuromyelitis optica (NMO) is an idiopathic inflammatory disorder of the central nervous
system (CNS) that preferentially affects the optic nerves and spinal cord. In Asia, NMO has …

Neuromyelitis optica

M Matiello, A Jacob, DM Wingerchuk… - Current opinion in …, 2007 - journals.lww.com
Clinical, radiologic, and immunologic features distinguish neuromyelitis optica from other
severe cases of multiple sclerosis. NMO-IgG is the first specific marker for a central nervous …

Neuromyelitis optica: a new perspective

SJ Pittock - Seminars in neurology, 2008 - thieme-connect.com
The traditional view of neuromyelitis optica (NMO) as a monophasic inflammatory disorder
that affects both the optic nerves and the spinal cord is expanding. Over the last decade, a …

Neuromyelitis optica spectrum disorder (NMOSD): A new concept

J De Seze, L Kremer, N Collongues - Revue neurologique, 2016 - Elsevier
The relationship between neuromyelitis optica (NMO) and multiple sclerosis (MS) has long
been controversial. NMO was previously considered a form of MS involving predominantly …

Long‐term MRI findings in neuromyelitis optica: seropositive versus seronegative patients

A Kıyat‐Atamer, E Ekizoğlu, E Tüzün… - European Journal of …, 2013 - Wiley Online Library
Background and purpose Neuromyelitis optica (NMO) is a severe demyelinating
inflammatory disorder associated with serum antibodies against aquaporin 4 (AQP 4‐Ab). A …

Current concept of neuromyelitis optica (NMO) and NMO spectrum disorders

A Jacob, A McKeon, I Nakashima, DK Sato… - Journal of Neurology …, 2013 - jnnp.bmj.com
Neuromyelitis optica (NMO) has been described as a disease clinically characterised by
severe optic neuritis (ON) and transverse myelitis (TM). Other features of NMO include …