Glaesserella parasuis serotype 5 induces pyroptosis via the RIG-I/MAVS/NLRP3 pathway in swine tracheal epithelial cells

Y Li, M Guo, Q Wang, H Zhou, W Wu, H Lin… - Veterinary Microbiology, 2024 - Elsevier
Glaesserella parasuis (G. parasuis) is a common Gram-negative commensal bacterium in
the upper respiratory tract of swine that can cause Glässer's disease under stress conditions …

Glaesserella parasuis serotype 4 HPS4-YC disrupts the integrity of the swine tracheal epithelial barrier and facilitates bacterial translocation

Q Wang, X Chang, M Liu, Q Lu, M Zhu, H Lin, H Fan - Veterinary Research, 2021 - Springer
Glaesserella parasuis (G. parasuis) is a commensal bacterium in the upper respiratory tract
of pigs that can also cause the swine Glässer disease, which induces an intensive …

Glaesserella parasuis induces inflammatory response in 3D4/21 cells through activation of NLRP3 inflammasome signaling pathway via ROS

X Luo, X Chang, H Zhou, H Lin, H Fan - Veterinary Microbiology, 2021 - Elsevier
Glaesserella parasuis (G. parasuis) is an important pathogenic bacterium that can cause
Glässer's disease, and it has resulted in tremendous economic losses to the global swine …

Glaesserella parasuis serotype 5 breaches the porcine respiratory epithelial barrier by inducing autophagy and blocking the cell membrane Claudin-1 replenishment

M Liu, Q Wang, W Wu, M Chen, P Zhang, M Guo… - PLoS …, 2022 - journals.plos.org
Glaesserella parasuis (G. parasuis), the primary pathogen of Glässer's disease, colonizes
the upper respiratory tract and can break through the epithelial barrier of the respiratory tract …

Sialylated Lipooligosaccharide Contributes to Glaesserella parasuis Penetration of Porcine Respiratory Epithelial Barrier

H Wang, W Wei, Q Cao, M Xu, Q Chen, Y Lv… - ACS Infectious …, 2021 - ACS Publications
Pathogens utilize various mechanisms to escape host immunological surveillance, break
down different tissue barriers, and cause infection. Sialylation is an important surface …

Upregulation of TLR4-Dependent ATP Production Is Critical for Glaesserella parasuis LPS-Mediated Inflammation

F Liu, Y Gao, J Jiao, Y Zhang, J Li, L Ding, L Zhang… - Cells, 2023 - mdpi.com
Glaesserella parasuis (G. parasuis), an important pathogenic bacterium, cause Glässer's
disease, and has resulted in tremendous economic losses to the global swine industry. G …

AMPK signaling pathway regulated the expression of the ApoA1 gene via the transcription factor Egr1 during G. parasuis stimulation

Y He, Y Peng, Y Sun, Y Wan, R Zhuo, S Hu… - Veterinary …, 2024 - Elsevier
Glaesserella parasuis (G. parasuis) is the causative agent of porcine Glässer's disease,
resulting in high mortality rates in pigs due to excessive inflammation-induced tissue …

PD-1/PD-L1 axis induced host immunosuppression via PI3K/Akt/mTOR signalling pathway in piglets infected by Glaesserella Parasuis

J Li, S Liu, Q Dong, Y Fu, Y Sun, R Luo, X Tian… - BMC Veterinary …, 2024 - Springer
Glaesserella parasuis, an important respiratory bacterial pathogen, causes Glässer's
disease in piglets, with potential immunosuppression. We established a piglet infection …

LRRC8A promotes Glaesserella parasuis cytolethal distending toxin-induced p53-dependent apoptosis in NPTr cells

W Mao, Z Wang, S Wen, Y Lin, J Gu, J Sun, H Wang… - Virulence, 2023 - Taylor & Francis
Glaesserella parasuis is an early colonizer of the swine upper respiratory tract and can
break through the respiratory barrier for further invasion. However, the mechanisms …

Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome

X Wang, M Liu, N Geng, Y Du, Z Li, X Gao, B Han… - Veterinary …, 2022 - Springer
Cell death and inflammation are intimately linked during mastitis due to Staphylococcus
aureus (S. aureus). Pyroptosis, a programmed necrosis triggered by gasdermin protein …