The protective role of curcumin in cardiovascular diseases

W Wongcharoen, A Phrommintikul - International journal of cardiology, 2009 - Elsevier
Curcumin (diferuloylmethane) is a polyphenol responsible for the yellow color of the curry
spice turmeric. It has been used in a variety of diseases in traditional medicine. Modern …

Signaling mechanisms of a water soluble curcumin derivative in experimental type 1 diabetes with cardiomyopathy

MTA Aziz, IN El Ibrashy, DP Mikhailidis… - Diabetology & metabolic …, 2013 - Springer
Background Curcumin exhibits anti-diabetic activities, induces heme-oxygenase-1 (HO-1)
and is an inhibitor of transcriptional co-activator p300. A novel water soluble curcumin …

Currying the heart: curcumin and cardioprotection

G Srivastava, JL Mehta - Journal of cardiovascular …, 2009 - journals.sagepub.com
Curcumin (diferuoylmethane) is the active ingredient of turmeric (curcuma longa). There has
been a surge of research in its anti-inflammatory and antioxidative properties, and its …

Curcumin, cardiometabolic health and dementia

Y Kim, P Clifton - International journal of environmental research and …, 2018 - mdpi.com
Current research indicates curcumin [diferuloylmethane; a polyphenolic compound isolated
from the rhizomes of the dietary spice turmeric (Curcuma longa)] exerts a beneficial effect on …

Curcumin protects against diabetic cardiomyopathy by promoting autophagy and alleviating apoptosis

Q Yao, Z Ke, S Guo, X Yang, F Zhang, X Liu… - Journal of molecular and …, 2018 - Elsevier
The effects of curcumin on regulating cardiac apoptosis and autophagy were analyzed in
diabetic models both in vivo and in vitro. In vivo, experimental diabetes was induced in mice …

Curcumin in heart failure: a choice for complementary therapy?

A Saeidinia, F Keihanian, AE Butler, RK Bagheri… - Pharmacological …, 2018 - Elsevier
Heart failure is a major public health concern and one of the most common reasons for a
cardiac hospital admission. Heart failure may be classified as having a reduced or …

Curcumin prevents diabetic cardiomyopathy in streptozotocin-induced diabetic rats: possible involvement of PKC–MAPK signaling pathway

V Soetikno, FR Sari, V Sukumaran… - European Journal of …, 2012 - Elsevier
The development of diabetic cardiomyopathy is accompanied with a high membrane-bound
protein kinase C (PKC) levels. Curcumin is a naturally occurring compound which is known …

Therapeutic effect of curcumin on metabolic diseases: evidence from clinical studies

Y Zeng, Y Luo, L Wang, K Zhang, J Peng… - International Journal of …, 2023 - mdpi.com
Metabolic diseases have become a serious threat to human health worldwide. It is crucial to
look for effective drugs from natural products to treat metabolic diseases. Curcumin, a …

Turmeric and its bioactive constituents trigger cell signaling mechanisms that protect against diabetes and cardiovascular diseases

HA Zhang, DD Kitts - Molecular and cellular biochemistry, 2021 - Springer
Turmeric, the rhizome of Curcuma longa plant belonging to the ginger family Zingiberaceae,
has a history in Ayurvedic and traditional Chinese medicine for treatment of chronic …

Cardioprotective effect of curcumin on myocardial ischemia/reperfusion injury: a meta-analysis of preclinical animal studies

YF Zeng, QH Guo, XY Wei, SY Chen, S Deng… - Frontiers in …, 2023 - frontiersin.org
Objective: This meta-analysis aimed to determine the efficacy of curcumin in preventing
myocardial ischemia/reperfusion (I/R) injury in animal models. Methods: Studies published …