Pharmacological and clinical properties of curcumin

CS Beevers, S Huang - Botanics: Targets and Therapy, 2011 - Taylor & Francis
The polyphenol natural product curcumin has been the subject of numerous studies over the
past decades, which have identified and characterized the compound's pharmacokinetic …

Efficacy and Safety of Curcumin Supplement on Improvement of Insulin Resistance in People with Type 2 Diabetes Mellitus: A Systematic Review and Meta‐Analysis …

T Zhang, Q He, Y Liu, Z Chen… - … Based Complementary and …, 2021 - Wiley Online Library
Background. Diabetes is a major public health concern. In addition, there is some evidence
to support curcumin as part of a diabetes treatment program. Methods. Data from …

Therapeutic applications of curcumin in diabetes: a review and perspective

C Quispe, J Herrera-Bravo, Z Javed… - BioMed Research …, 2022 - Wiley Online Library
Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug
therapy as well as lifestyle changes. There is now growing scientific evidence to support the …

Curcumin anti-diabetic effect mainly correlates with its anti-apoptotic actions and PI3K/Akt signal pathway regulation in the liver

Z Xia, S Zhang, Y Chen, K Li, W Chen, Y Liu - Food and Chemical …, 2020 - Elsevier
This study aimed to investigate the therapeutic effect of curcumin on type 2 diabetes and its
underlying mechanisms. A type 2 diabetes mellitus rat model was established by providing …

[HTML][HTML] Differential effects of curcumin on vasoactive factors in the diabetic rat heart

H Farhangkhoee, ZA Khan, S Chen… - Nutrition & metabolism, 2006 - Springer
Background Increased oxidative stress has been associated with the pathogenesis of
chronic diabetic complications, including cardiomyopathy. Recent studies indicate that …

Inhibition of JNK phosphorylation by a novel curcumin analog prevents high glucose–induced inflammation and apoptosis in cardiomyocytes and the development of …

Y Pan, Y Wang, Y Zhao, K Peng, W Li, Y Wang… - Diabetes, 2014 - Am Diabetes Assoc
Hyperglycemia-induced inflammation and apoptosis have important roles in the
pathogenesis of diabetic cardiomyopathy. We recently found that a novel curcumin …

Biological and pharmacological effects of hexahydrocurcumin, a metabolite of curcumin

Y Huang, S Cao, Q Zhang, H Zhang, Y Fan… - Archives of biochemistry …, 2018 - Elsevier
Curcumin, one of the most precious pharmacologically relevant natural products, has gained
considerable attention among scientists for decades because of its multi-pharmacological …

[HTML][HTML] Curcumin as a natural remedy for atherosclerosis: a pharmacological review

L Singh, S Sharma, S Xu, D Tewari, J Fang - Molecules, 2021 - mdpi.com
Curcumin, a natural polyphenolic compound present in Curcuma longa L. rhizomes, shows
potent antioxidant, anti-inflammatory, anti-cancer, and anti-atherosclerotic properties …

The pharmacological basis of the curcumin nutraceutical uses: An update

D Canistro, A Chiavaroli, D Cicia, F Cimino, D Curro… - Pharmadvances, 2021 - air.unimi.it
Curcumin is the major phytoconstituent found in the rhizomes of Curcuma longa L.
Preparations derived from the rhizome of the plant, referred as turmeric, have been used for …

Effects of curcumin consumption on human chronic diseases: A narrative review of the most recent clinical data

M Mantzorou, E Pavlidou, G Vasios… - Phytotherapy …, 2018 - Wiley Online Library
Numerous clinical trials have investigated the potential beneficial effects of curcumin
supplementation against several human chronic diseases. Up to now, it has been claimed …