Attenuation of ischemic brain edema and cerebrovascular injury after ischemic preconditioning in the rat

T Masada, Y Hua, G Xi, SR Ennis… - Journal of Cerebral …, 2001 - journals.sagepub.com
Ischemic preconditioning (IPC) induces neuroprotection to subsequent severe ischemia, but
its effect on the cerebrovasculature has not been studied extensively. This study evaluated …

AKT/GSK 3β‐dependent autophagy contributes to the neuroprotection of limb remote ischemic postconditioning in the transient cerebral ischemic rat model

ZF Qi, YM Luo, XR Liu, RL Wang… - CNS neuroscience & …, 2012 - Wiley Online Library
Background Limb remote ischemic postconditioning (RIP ost C) has been recognized as an
applicable strategy in protecting against cerebral ischemic injury. However, the time window …

[HTML][HTML] Limb remote ischemic conditioning: mechanisms, anesthetics, and the potential for expanding therapeutic options

G Chen, M Thakkar, C Robinson, S Doré - Frontiers in neurology, 2018 - frontiersin.org
Novel and innovative approaches are essential in developing new treatments and improving
clinical outcomes in patients with ischemic stroke. Remote ischemic conditioning (RIC) is a …

Postconditioning-induced neuroprotection, mechanisms and applications in cerebral ischemia

YY Fan, WW Hu, F Nan, Z Chen - Neurochemistry international, 2017 - Elsevier
Ischemic postconditioning (PostC) is defined as a series of rapid intermittent interruptions of
blood flow at the phase of reperfusion, which produces neuroprotection against cerebral …

Remote ischemic perconditioning in thrombolysed stroke patients: randomized study of activating endogenous neuroprotection–design and MRI measurements

KD Hougaard, N Hjort, D Zeidler… - … Journal of Stroke, 2013 - journals.sagepub.com
Background Intravenous administration of alteplase is the only approved treatment for acute
ischemic stroke. Despite the effectiveness of this treatment, 50% of patients suffer chronic …

The effect of repeated remote ischemic postconditioning after an ischemic stroke (REPOST): A randomized controlled trial

TRJ Landman, Y Schoon, MC Warlé… - … Journal of Stroke, 2023 - journals.sagepub.com
Background and Aims: A potential strategy to treat ischemic stroke may be the application of
repeated remote ischemic postconditioning (rIPostC). This consists of several cycles of brief …

Remote ischemic conditioning and stroke recovery

MW McDonald, A Dykes, MS Jeffers… - … and Neural Repair, 2021 - journals.sagepub.com
Remote ischemic conditioning (RIC) is a noninvasive procedure whereby several periods of
ischemia are induced in a limb. Although there is growing interest in using RIC to improve …

Peripheral vascular disease as remote ischemic preconditioning, for acute stroke

M Connolly, A Bilgin-Freiert, B Ellingson… - Clinical neurology and …, 2013 - Elsevier
Objectives Remote ischemic preconditioning (RIPC) is a powerful endogenous mechanism
whereby a brief period of ischemia is capable of protecting remote tissues from subsequent …

[HTML][HTML] Cerebral protection by remote ischemic post-conditioning in patients with ischemic stroke: a systematic review and meta-analysis of randomized controlled …

M Lu, Y Wang, X Yin, Y Li, H Li - Frontiers in Neurology, 2022 - frontiersin.org
Background There is evidence that remote limb ischemic postconditioning (RIPostC) can
reduce ischemia-reperfusion injury (IRI) and improve the prognosis of patients with ischemic …

[HTML][HTML] Remote ischemic conditioning attenuates oxidative stress and inflammation via the Nrf2/HO-1 pathway in MCAO mice

YY Sun, HJ Zhu, RY Zhao, SY Zhou, MQ Wang, Y Yang… - Redox biology, 2023 - Elsevier
The protective effects of remote ischemic conditioning (RIC) on acute ischemic stroke have
been reported. However, the protective mechanisms of RIC have not been fully elucidated …