The respiratory threat posed by multidrug resistant G ram‐negative bacteria

A Rodrigo‐Troyano, O Sibila - Respirology, 2017 - Wiley Online Library
Respiratory infections are a major cause of global mortality and morbidity. In recent years,
an increased incidence of multidrug‐resistant (MDR) Gram‐negative bacteria (GNB) has …

Potentially multidrug-resistant non-fermentative Gram-negative pathogens causing nosocomial pneumonia

AM Ferrara - International journal of antimicrobial agents, 2006 - Elsevier
Owing to its high morbidity and mortality, nosocomial pneumonia represents a particularly
serious illness and one of the most frequent complications in ventilated patients admitted to …

Multidrug-resistant gram-negative bacterial infections in the hospital setting: overview, implications for clinical practice, and emerging treatment options

E Cerceo, SB Deitelzweig, BM Sherman… - Microbial Drug …, 2016 - liebertpub.com
The increasing prevalence of infections due to multidrug-resistant (MDR) gram-negative
bacteria constitutes a serious threat to global public health due to the limited treatment …

Multi-drug resistant gram-negative bacterial pneumonia: etiology, risk factors, and drug resistance patterns

M Assefa - Pneumonia, 2022 - Springer
Bacterial pneumonia is one of the most serious public health issues owing to its medical and
economic costs, which result in increased morbidity and mortality in people of all ages …

Changing epidemiology and decreased mortality associated with carbapenem-resistant gram-negative bacteria, 2000–2017

A Babiker, LG Clarke, M Saul, JA Gealey… - Clinical Infectious …, 2021 - academic.oup.com
Background Carbapenem-resistant gram-negative bacteria (CRGNB) continue to present a
global healthcare crisis. We aimed to identify emerging trends of CRGNB over nearly 2 …

Pandrug resistance (PDR), extensive drug resistance (XDR), and multidrug resistance (MDR) among Gram-negative bacilli: need for international harmonization in …

ME Falagas… - Clinical infectious diseases, 2008 - academic.oup.com
It should also be noted that, in the proposed definitions [1], a category of highly resistant
pathogens, with resistance patterns intermediate to those described in the authors' …

Treatment of bloodstream infections due to Gram-negative bacteria with difficult-to-treat resistance

M Bassetti, A Vena, C Sepulcri, DR Giacobbe… - Antibiotics, 2020 - mdpi.com
The rising incidence of bloodstream infections (BSI) due to Gram-negative bacteria (GNB)
with difficult-to-treat resistance (DTR) has been recognized as a global emergency. The aim …

Treatment of infections caused by multidrug-resistant gram-negative bacteria: Report of the British society for antimicrobial chemotherapy/healthcare infection society …

PM Hawkey, RE Warren, DM Livermore… - Journal of …, 2018 - academic.oup.com
Abstract The Working Party makes more than 100 tabulated recommendations in
antimicrobial prescribing for the treatment of infections caused by multidrug-resistant (MDR) …

Emerging resistant Gram-negative aerobic bacilli in hospital-acquired infections

AN Kunz, I Brook - Chemotherapy, 2010 - karger.com
The increasing emergence of serious multidrug-resistant (MDR) Gram-negative infections
has led to a new health-care crisis. These infections predominately include MDR …

The threat of multidrug-resistant/extensively drug-resistant Gram-negative respiratory infections: another pandemic

D Reynolds, JP Burnham, CV Guillamet… - European …, 2022 - Eur Respiratory Soc
Antibiotic resistance is recognised as a global threat to human health by national healthcare
agencies, governments and medical societies, as well as the World Health Organization …