METHODS This study is based on the results of 18 experiments on the heart-lung
preparation of the dog (HLP). The animals had an average weight of 10.4 kg.(7.3-14.6), 15 …

METHODS The experiments were carried out in dogs under dial urethane anaesthesia and
in spinal cats. In order to exclude vagal effects atropine was given and, in the dog, the vagi …

As already reported (Briggs, Nature, 1939, lM, 247), analytical data now agree with formulae
C45H, 3016N and C,, H, O, N for solasonine and solasodine respectively. These formulze …

Fate and distribution studies using tritiated solanine in rats showed that the compound (1) is
poorly absorbed from the gastrointestinal tract,(2) is rapidly eliminated in the urine and …

The family Solanacea comprises about 75 genera and 1750 species (l), the majority of
which cptain either alkaloids or glucosides. Among this large number are two, tiz., Solunum …

The glycosidic alkaloids of the fruit of S. Zaciniatum Ait., S. nodiflorum Jacq.(forms A and B),
S. miniaturn Bernh., S.“simile,” S. gracile Otto, S. douglasii Dun., and S. nigrum L. have been …

HO A/'(I.) the second assumption is correct, there is no alternative structure for the
heterocyclic ring system to that proposed. If, however, there is more than one point of …

IN Part V (J., 1950, 3013) formula (I) was proposed for solasodine. N-Nitroso-derivatives
were prepared from solasodine and some of its derivatives, indicating the presence of a …

It may be suggested in passing that, since solasodine differs from solanidine only by an
additional oxygen atom and since also solasonine and solanine are similarly built up from …

4646 Briggs, Cambie, and Hoare: were shown to be solasonine and solamargine by
chromatographic comparison with authentic samples. The same alkaloids were also shown …