[HTML][HTML] Development and research progress of anti-drug resistant fungal drugs

X Cui, L Wang, Y Lue, C Yue - Journal of Infection and Public Health, 2022 - Elsevier
With the widespread use of immunosuppressive agents and the increase in patients with
severe infections, the incidence of fungal infections worldwide has increased year by year …

Potential targets for the development of new antifungal drugs

H Su, L Han, X Huang - The journal of antibiotics, 2018 - nature.com
In recent years, incidences of invasive fungal infections have greatly increased, especially in
immunosuppressed patients, but most today's antifungal drugs are not completely effective …

[HTML][HTML] Antifungals and drug resistance

CM Hossain, LK Ryan, M Gera, S Choudhuri, N Lyle… - Encyclopedia, 2022 - mdpi.com
Definition Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …

How urgent is the need for new antifungals?

AG Stewart, DL Paterson - Expert Opinion on Pharmacotherapy, 2021 - Taylor & Francis
Introduction: Invasive fungal infection carries a high morbidity, mortality and economic cost.
In recent times, a rising incidence of fungal infection and antifungal resistance is occurring …

Novel agents and drug targets to meet the challenges of resistant fungi

MW McCarthy, DP Kontoyiannis… - The Journal of …, 2017 - academic.oup.com
The emergence of drug-resistant fungi poses a major threat to human health. Despite
advances in preventive, diagnostic, and therapeutic interventions, resistant fungal infections …

New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics

J Geddes‐McAlister, RS Shapiro - … of the New York Academy of …, 2019 - Wiley Online Library
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …

[HTML][HTML] Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium

A Arastehfar, T Gabaldón, R Garcia-Rubio, JD Jenks… - Antibiotics, 2020 - mdpi.com
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …

[HTML][HTML] Antifungal drug discovery: new theories and new therapies

CJ Seneviratne, EAR Rosa - Frontiers in microbiology, 2016 - frontiersin.org
Medically important fungal infections can be broadly classified into superficial surface
infections and invasive mycoses (Samaranayake and MacFarlane, 1990; Roemer and …

Antifungal drugs: the current armamentarium and development of new agents

N Robbins, GD Wright, LE Cowen - Microbiology spectrum, 2016 - Am Soc Microbiol
Invasive fungal infections are becoming an increasingly important cause of human mortality
and morbidity, particularly for immunocompromised populations. The fungal pathogens …

[HTML][HTML] Potential strategies to control the risk of antifungal resistance in humans: A comprehensive review

AA Rabaan, T Sulaiman, SH Al-Ahmed, ZA Buhaliqah… - Antibiotics, 2023 - mdpi.com
Fungal infections are becoming one of the main causes of morbidity and mortality in people
with weakened immune systems. Mycoses are becoming more common, despite greater …