From the publisher's website: Infections caused by pathogenic fungi are a significant global
problem: a situation exacerbated by the limited availability of good antifungal options. Being …

Invasive fungal infections are a frequent and important complication of modern medicine
and remain important causes of morbidity and mortality, particularly in immunocompromised …

The evolution of antifungal resistance among fungal pathogens has rendered the limited
arsenal of antifungal drugs futile. Considering the recent rise in the number of nosocomial …

The global impact of fungal infections on human health has recently been highlighted by
several important publications, 1, 2 and advocacy groups. 3 Although several factors …

Introduction: Invasive fungal infections (IFIs) pose significant morbidity and are often life-
threatening to many high-risk patients. Timely diagnosis and treatment of these infections …

This book is designed to provide a comprehensive but insightful examination of antifungal
therapy in the changing clinical milieu of modern medicine. It is an update from the original …

Clinically available antifungals for the treatment of invasive fungal infections primarily target
either ergosterol in the fungal cell membrane or 1, 3-β-D-glucan in the fungal cell wall …

Antifungal resistance represents a major clinical challenge to clinicians responsible for
treating invasive fungal infections due to the limited arsenal of systemically available …

The use of antifungal drugs started in the 1950s with polyenes nystatin, natamycin and
amphotericin B-deoxycholate (AmB). Until the present day, AmB has been considered to be …

Invasive fungal infections continue to appear in record numbers as the
immunocompromised population of the world increases, owing partially to the increased …