ADAMTS proteins are a superfamily of 26 secreted molecules comprising two related, but
distinct families. ADAMTS proteases are zinc metalloendopeptidases, most of whose …

The mammalian ADAMTS superfamily comprises 19 secreted metalloproteinases and 7
ADAMTS-like proteins, each the product of a distinct gene. Thus far, all appear to be relevant …

ADAMTS designates a family of 19 secreted enzymes, whose the first member ADAMTS1
was described in 1997. The ADAMTS family has a role in extracellular matrix degradation …

Abstract Background The ADAMTS (A Disintegrin-like and Metalloprotease with
Thrombospondin motifs) proteins are a family of metalloproteases with sequence similarity …

Objective To phenotypically characterize ADAMTS‐4–and ADAMTS‐5–double‐knockout
mice, and to determine the effect of deletion of ADAMTS‐4 and ADAMTS‐5 on the …

The'A-disintegrin and metalloproteinase'(ADAM) and'A-disintegrin and metalloproteinase
with thrombospondin motifs'(ADAMTS) genes make up two similar, yet distinct, gene …

Comparison of domain structures of ADAMTSs, ADAMs and SVMPs. The first three boxes of
each bar represent, respectively, the common prodomain and the metalloprotease and …

We describe the discovery and characterization of ADAMTS10, a novel metalloprotease
encoded by a locus on human chromosome 19 and mouse chromosome 17. ADAMTS10 …

The ADAMTS (a disintegrin-like and metalloproteinase domain with thrombospondin type I
motifs) family of proteases plays a role in pathological conditions including arthritis, cancer …

The ADAMTSs (ad isintegrin a nd m etalloproteinase with t hrombo s pondin motifs) are a
group of proteases that are found both in mammals and invertebrates. Since the prototype …