Since the detection of nitric oxide two and a half decades ago, there has been an incredible
boost in endothelial function research, which is fascinating the research community …

The endothelium is more than just a passive interface between the blood and the vessel
wall. Since the pioneering discovery of nitric oxide as an important endothelium-derived …

The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

Vascular endothelium plays a key role in the local regulation of vascular tone and vascular
architecture by release of vasodilator and vasoconstrictor substances, as well as factors with …

The endothelium controls the tone of the underlying vascular smooth muscle mainly through
the production of vasodilator mediators. In some cases, this function is hampered by the …

The vascular endothelium plays a key role in the local regulation of vascular tone by the
release of vasodilator substances (ie endothelium-derived relaxing factor (EDRF= nitric …

Vascular endothelium is responsible for the secretion of several substances exerting anti-
atherogenic effects. Endothelial damage is also crucial for the progress of atherosclerosis …

The endothelium mediates a number of responses (relaxation or contraction) of arteries and
veins from animals and humans. The endothelium-dependent relaxations are due to the …

The endothelium plays important roles in modulating vascular tone by synthesizing and
releasing a variety of endothelium-derived relaxing factors, including vasodilator …

The endothelium is a crucial regulator of vascular physiology, producing in healthy
conditions several substances with a potent antiatherosclerotic properties. Accordingly, the …